THE ION FUNNEL: THEORY, IMPLEMENTATIONS, AND APPLICATIONS

被引：226

作者：

Kelly, Ryan T. ^{[1
]}

Tolmachev, Aleksey V. ^{[1
]}

Page, Jason S. ^{[1
]}

Tang, Keqi ^{[1
]}

Smith, Richard D. ^{[1
]}

机构：

[1] Pacific NW Natl Lab, Div Biol Sci, Richland, WA 99352 USA

来源：

MASS SPECTROMETRY REVIEWS | 2010年 / 29卷 / 02期

关键词：

ion optics; rf focusing; ion guide; multipole ion guide; stacked ring ion guide; ESI; IONIZATION MASS-SPECTROMETRY; SENSITIVITY ELECTROSPRAY-IONIZATION; SOLVENT-FREE ENVIRONMENT; TREATED METAL-SURFACE; ATMOSPHERIC-PRESSURE; GAS-PHASE; MOBILITY SPECTROMETRY; MULTICAPILLARY INLET; RAMAN-SPECTROSCOPY; EMITTER ARRAYS;

D O I：

10.1002/mas.20232

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The electrodynamic ion funnel enabled the manipulation and focusing of ions in a pressure regime (0.1-30 Torr) that has challenged traditional appraoches, and provided the basis for much greater mass spectrometer ion transmission efficiencies. The initial ion funnel implementations aimed to efficiently capture ions in the expanding gas jet of an electrospray ionization interface and radially focus them for efficient transfer through a conductance limiting orifice. We review the improvements in fundamental understanding of ion motion in ion funnels, the evolution in its implementations that have brought the ion funnel to its current state of refinement, as well as applications of the ion funnel for purposes such as ion trapping, ion cooling. low pressure electrospray, and ion mobility spectrometry. (C) 2009 Wiley periodicals. Inc., Mass Spec Rev 29: 294-312, 2010

引用

页码：294 / 312

页数：19

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