Transverse Myelitis

被引:117
作者
Frohman, Elliot M. [1 ,2 ]
Wingerchuk, Dean M. [3 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Dept Neurol, Dallas, TX 75235 USA
[2] Univ Texas SW Med Ctr Dallas, Dept Ophthalmol, Dallas, TX 75235 USA
[3] Mayo Clin, Dept Neurol, Scottsdale, AZ USA
关键词
MULTIPLE-SCLEROSIS; NEUROMYELITIS-OPTICA; PLASMA-EXCHANGE; DOUBLE-BLIND; NEUROPATHIC PAIN; EFFICACY; FATIGUE; CORTICOSTEROIDS; MODAFINIL; DIAGNOSIS;
D O I
10.1056/NEJMcp1001112
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
An otherwise healthy 28-year-old woman presents to the emergency department with progressive weakness that began 3 days earlier. She reports difficulty walking, numbness in the body below her breasts, and urinary urgency, and she notes that neck flexion triggers an electrical sensation that radiates to the coccyx. Physical examination reveals moderate paraparesis with hyperreflexia, a left extensor plantar response, impairment of vibratory and proprioceptive sensation, and a sensory level at T6. Magnetic resonance imaging (MRI) reveals a lower cervical cord lesion that enhances after gadolinium administration, a finding that is consistent with transverse myelitis. How should she be further evaluated and treated?
引用
收藏
页码:564 / 572
页数:9
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