Massarilactones E-G, new metabolites from the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima

被引：45

作者：

Krohn, Karsten

Zia-Ullah

Hussain, Hidayat

Floerke, Ulrich

Schulz, Barbara

Draeger, Siegfried

Pescitelli, Gennaro

Salvadori, Piero

Antus, Sandor

Kurtan, Tibor

机构：

[1] Univ Gesamthsch Paderborn, Dept Chem, D-33098 Paderborn, Germany

[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Mikrobiol, D-31806 Braunschweig, Germany

[3] Univ Pisa, Dipartimento Chim & Chim Ind, I-56126 Pisa, Italy

[4] Univ Debrecen, Dept Organ Chem, H-4010 Debrecen, Hungary

[5] Hungarian Acad Sci, Res Grp Carbohydrates, H-4010 Debrecen, Hungary

来源：

CHIRALITY | 2007年 / 19卷 / 06期

关键词：

fungal metabolites; Coniothyrium sp; structure elucidation; massarilactones; X-ray analysis; solid-state CD-TDDFF method;

D O I：

10.1002/chir.20402

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new massarilactones E-G (1-3) and the massarilactone acetonide (4) were isolated from the ethyl acetate extract of the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima. Their structures were determined by analysis of the 1D and 2D NMR and mass spectroscopic data. The structure of massarilactones E (1) was confirmed by X-ray diffraction analysis, and its absolute configuration determined by the solid-state CD/TDDFT method. (C) 2007 Wiley-Liss, Inc.

引用

页码：464 / 470

页数：7

共 24 条

[11]

KOCK I, 2007, IN PRESS EUR J ORG C

[12]

KROHN K, 2007, IN PRESS EUR J ORG C

[13] Bioactive natural products from the endophytic fungus Ascochyta sp from Meliotus dentatus -: Configurational assignment by solid-state CD and TDDFT calculations [J].