Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography

被引：22
作者：
Campisi, Roxana [1 ,2 ]
Marengo, Fernando D. [3 ]
机构：
[1] Diagnost Maipu, Dept Nucl Med & Cardiovasc Imaging, Buenos Aires, DF, Argentina
[2] Inst Argentino Diagnost & Tratamiento SA, Dept Nucl Med, Buenos Aires, DF, Argentina
[3] Univ Buenos Aires, Lab Fisiol & Biol Mol, Inst Fisiol Biol Mol & Neurociencias CONICET, Dept Fisiol & Biol Mol & Celular,Fac Ciencias Exa, Buenos Aires, DF, Argentina
来源：
CARDIOVASCULAR DIAGNOSIS AND THERAPY | 2017年 / 7卷 / 02期
关键词：
Women; ischemic heart disease (IHD); positron emission tomography (PET); coronary flow reserve (CFR); MYOCARDIAL BLOOD-FLOW; SYNDROME EVALUATION WISE; COLD PRESSOR TEST; CARDIAC PET SUMMIT; ARTERY-DISEASE; CARDIOVASCULAR EVENTS; POSTMENOPAUSAL WOMEN; ADVERSE OUTCOMES; CHEST-PAIN; SHORT-TERM;
D O I：
10.21037/cdt.2017.04.08
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Traditional approaches for risk assessment of ischemic heart disease (IHD) are based on the physiological consequences of an epicardial coronary stenosis. Of note, normal coronary arteries or nonobstructive coronary artery disease (CAD) is a common finding in women with signs and symptoms of ischemia. Therefore, assessment of risk based on a coronary stenosis approach may fail in women. Positron emission tomography (PET) quantifies absolute myocardial blood flow (MBF) which may help to elucidate other mechanisms involved such as endothelial dysfunction and alterations in the smooth muscle cell relaxation responsible for IHD in women. The objective of the present review is to describe the current state of the art of PET imaging in assessing IHD in women with nonobstructive CAD.
引用
收藏
页码：196 / 205
页数：10
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