Assembly of nanoparticle-protein binding complexes:: From monomers to ordered arrays

被引:41
作者
Hu, Minghui [1 ]
Qian, Luping [1 ]
Brinas, Raymond P. [1 ]
Lymar, Elena S. [1 ]
Hainfeld, James F. [1 ]
机构
[1] Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USA
关键词
electron microscopy; hybrid materials; nanoparticles; proteins; self-assembly;
D O I
10.1002/anie.200701180
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Tag it: Well-defined monomers, dimers, trimers, three-dimensional spherical shells, and two-dimensional ordered arrays of genetically engineered proteins were constructed by using functionalized gold nanoparticles. Nanoparticle size, functionality, and protein genetic motif contribute to the unique geometry, precise stoichiometry, given orientation, and high specificity of these nanoparticle-protein hybrid structures. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:5111 / 5114
页数:4
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