Blastic plasmacytoid dendritic cell leukemia in a black malian

被引：0

作者：

Diallo, Y. L. ^{[1
]}

Cucherousset, J. ^{[2
]}

Samassekou, O. ^{[3
]}

Doumbere, M. ^{[1
]}

Cissoko, Y. ^{[4
]}

Menta, D. T. ^{[1
]}

Ouologuem, N. ^{[1
]}

Ouologuem, M. ^{[1
]}

Konate, M. ^{[1
]}

Sidibe, A. T. ^{[1
]}

机构：

[1] Hop Mali, Serv Med, Bamako, Mali

[2] GHI Le RAINCY, Serv Pathol, Montfermeil, France

[3] INSERM, Paris, France

[4] Hop GAO, Serv Med, Sossokoira Gao, Mali

来源：

NIGERIAN JOURNAL OF CLINICAL PRACTICE | 2017年 / 20卷 / 06期

关键词：

Acute Leukemia; black african; dendritic cell; Mali; NEOPLASM;

D O I：

10.4103/1119-3077.208955

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive hematologic malignancy, that most commonly manifests as cutaneous lesions. A 19-year-old Malian female was admitted to the Unit of Medicine of Hopital du Mali with anemia, fever, weakness, and weight loss. On physical examination she was wasted, pale, febrile (37.4(degrees)C), and had inguinal and axillary lymphadenopathies. The complete blood count found pancytopenia with Hemoglobin level of 4.8 g/dL, Leucocytes count of 1900/mL (neutrophil: 300/mL), and platelets count of 56 000/mL. The ultrasonographic examination found hepatomegaly and splenomegaly. The bone marrow biopsy and flow cytometer analysis were in keeping with a diagnosis of BPDCN. The patient, unfortunately, was lost four months later after her hospital admission due to late diagnosis by septicemia. The early diagnosis and availability of specific drugs for acute leukemia could improve the clinical outcome of patients with BPDCN in Mali.

引用

页码：777 / 781

页数：5