Human Immunodeficiency Virus Pre-Exposure Prophylaxis: Use of Emtricitabine/Tenofovir Alafenamide

被引:3
作者
Blackwell, Christopher W. [1 ]
Castillo, Humberto Lopez [2 ]
机构
[1] Univ Cent Florida, Adult Gerontol Acute Care Nurse Practitioner Prog, Coll Nursing, Orlando, FL 32816 USA
[2] Univ Cent Florida, Dept Hlth Sci, Coll Hlth Profess & Sci, Coll Med, Orlando, FL 32816 USA
来源
JNP-JOURNAL FOR NURSE PRACTITIONERS | 2021年 / 17卷 / 06期
关键词
AIDS; emtricitabine; tenofovir alafenamide; human immunodeficiency virus; human immunodeficiency virus prevention; pre-exposure prophylaxis; PREVENTING HIV;
D O I
10.1016/j.nurpra.2021.01.002
中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
Pre-exposure prophylaxis (PrEP) involves the use of antiretroviral medication in concert with safer sex practices to significantly reduce the risk of type 1 human immunodeficiency virus infection. In October 2019, daily use of emtricitabine/tenofovir alafenamide (FTC/TAF) 200 mg/25 mg was approved as a newer agent for PrEP to prevent HIV-1 infection in at-risk adults and adolescents. The purpose of this article is to: 1) provide an overview of the FTC/TAF regimen and its safety and efficacy profiles, 2) discuss indications and contra-indications of FTC/TAF as PrEP, 3) provide a focused comparison of FTC/TDF with FTC/TAF, and 4) examine issues surrounding cost and accessibility in the United States. (c) 2021 Elsevier Inc. All rights reserved.
引用
收藏
页码:673 / 676
页数:4
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