Protective Effects of Exercise on Cognition and Brain Health in Older Adults

被引:68
作者
Tyndall, Amanda V. [1 ,2 ]
Clark, Cameron M. [1 ,2 ]
Anderson, Todd J. [3 ,4 ]
Hogan, David B. [2 ,5 ,6 ,7 ]
Hill, Michael D. [2 ,5 ,6 ]
Longman, R. S. [2 ,8 ,9 ]
Poulin, Marc J. [1 ,2 ,4 ,5 ,10 ,11 ]
机构
[1] Univ Calgary, Dept Physiol & Pharmacol, Calgary, AB, Canada
[2] Univ Calgary, Hotchkiss Brain Inst, Calgary, AB, Canada
[3] Univ Calgary, Dept Cardiac Sci, Calgary, AB, Canada
[4] Univ Calgary, Libin Cardiovasc Inst Alberta, Calgary, AB, Canada
[5] Univ Calgary, Dept Clin Neurosci, Calgary, AB, Canada
[6] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
[7] Univ Calgary, Dept Med, Calgary, AB, Canada
[8] Univ Calgary, Dept Psychol, Calgary, AB, Canada
[9] Alberta Hlth Serv, Foothills Med Ctr, Psychol Serv, Calgary, AB, Canada
[10] Univ Calgary, Fac Kinesiol, Calgary, AB, Canada
[11] Univ Calgary, OBrien Inst Publ Hlth, Cumming Sch Med, Calgary, AB, Canada
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2018年 / 46卷 / 04期
关键词
exercise dose; cerebrovascular function; cognitive function; aging; intervention; CEREBRAL-BLOOD-FLOW; POPULATION-BASED COHORT; PHYSICAL-ACTIVITY; ALZHEIMERS-DISEASE; ALCOHOL-CONSUMPTION; METABOLIC SYNDROME; US ADULTS; IN-MOTION; RISK; ASSOCIATION;
D O I
10.1249/JES.0000000000000161
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Accelerated trajectories of cognitive decline in older adults may increase the risk of developing Alzheimer disease and related dementias (ADRD). Physical activity has potential modifying effects on these changes that could prevent or delay ADRD. This review explores the hypothesis that multiple, mutually complimentary, and interacting factors explain the positive association between exercise and the optimization of cognition in older adults.
引用
收藏
页码:215 / 223
页数:9
相关论文
共 53 条
  • [1] [Anonymous], 2015, Canadian Cancer Statistics 2015, P1
  • [2] Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    Atkinson, AJ
    Colburn, WA
    DeGruttola, VG
    DeMets, DL
    Downing, GJ
    Hoth, DF
    Oates, JA
    Peck, CC
    Schooley, RT
    Spilker, BA
    Woodcock, J
    Zeger, SL
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2001, 69 (03) : 89 - 95
  • [3] Exercise and mood: A selective review and synthesis of research employing the profile of mood states
    Berger, BG
    Motl, RW
    [J]. JOURNAL OF APPLIED SPORT PSYCHOLOGY, 2000, 12 (01) : 69 - 92
  • [4] Low Cerebral Blood Flow is Associated with Lower Memory Function in Metabolic Syndrome
    Birdsill, Alex C.
    Carlsson, Cynthia M.
    Willette, Auriel A.
    Okonkwo, Ozioma C.
    Johnson, Sterling C.
    Xu, Guofan
    Oh, Jennifer M.
    Gallagher, Catherine L.
    Koscik, Rebecca L.
    Jonaitis, Erin M.
    Hermann, Bruce P.
    LaRue, Asenath
    Rowley, Howard A.
    Asthana, Sanjay
    Sager, Mark A.
    Bendlin, Barbara B.
    [J]. OBESITY, 2013, 21 (07) : 1313 - 1320
  • [5] Bouazizw W, 2016, AUSTIN SPORT MED, V1, P2
  • [6] Effects of cardiorespiratory fitness and cerebral blood flow on cognitive outcomes in older women
    Brown, Allison D.
    McMorris, Carly A.
    Longman, R. Stewart
    Leigh, Richard
    Hill, Michael D.
    Friedenreich, Christine M.
    Poulin, Marc J.
    [J]. NEUROBIOLOGY OF AGING, 2010, 31 (12) : 2047 - 2057
  • [7] Total daily physical activity and the risk of AD and cognitive decline in older adults
    Buchman, A. S.
    Boyle, P. A.
    Yu, L.
    Shah, R. C.
    Wilson, R. S.
    Bennett, D. A.
    [J]. NEUROLOGY, 2012, 78 (17) : 1323 - 1329
  • [8] Physical activity, exercise, and inflammatory markers in older adults: Findings from the health, aging and body composition study
    Colbert, LH
    Visser, M
    Simonsick, EM
    Tracy, RP
    Newman, AB
    Kritchevsky, SB
    Pahor, M
    Taaffe, DR
    Brach, J
    Rubin, S
    Harris, TB
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2004, 52 (07) : 1098 - 1104
  • [9] Cotman CW, 2007, TRENDS NEUROSCI, V30, P464, DOI 10.1016/j.tins.2007.06.011
  • [10] Davenport MH, 2012, EXERC SPORT SCI REV, V40, P153, DOI 10.1097/JES.0b013e3182553430