Is Omicron the end of pandemic or start of a new innings?

被引:24
作者
Das, Swarnali [1 ]
Samanta, Sovan [1 ]
Banerjee, Jhimli [1 ]
Pal, Amitava [2 ]
Giri, Biplab [1 ]
Kar, Suvrendu Sankar [3 ]
Dash, Sandeep Kumar [1 ]
机构
[1] Univ Gour Banga, Dept Physiol, Malda 732103, W Bengal, India
[2] City Coll, Dept Physiol, 102-1 Raja Rammohan Sarani, Kolkata 700009, W Bengal, India
[3] RG Kar Med Coll & Hosp, Dept Med, Kolkata 700004, W Bengal, India
基金
英国科研创新办公室;
关键词
Omicron; Delta; VOC; Mutation; Natural vaccine; SARS-CoV-2; VARIANT; VIRUS;
D O I
10.1016/j.tmaid.2022.102332
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In the middle of November 2021, Omicron (B.1.1.529), a novel variant of SARS-CoV-2 was identified in South Africa. Owing to continuous increasing cases with rapid transmissibility and immune evasion, the World Health Organization (WHO) has categorized this strain as a variant of concern (VOC). In total, over 60 mutations have been identified in Omicron (BA.1) and latterly, its three sub-lineages (BA.1.1, BA.2, and BA.3) have also been found with additional mutations and pathogenicity. The highly contagious Omicron causes less severe sickness than Delta, but it is still dangerous for those who have not been vaccinated. Following the unique identification of the Omicron variant, a fresh debate has erupted regarding the natural vaccines. A number of experts believe that Omicron can work as a natural vaccine, because it is similar to live attenuated vaccines in certain ways. Additionally, it was highlighted that the high rate of antibody generation in individuals cured of Omicron provide suggestive evidence in favor of those researchers who claimed Omicron acts as natural vaccine. Some disagreements also noted, as it also has tremendous health effects and high infection rate, as similar to the prior variants. This review summarizes the contradictory scenario among the scientists about Omicron variant.
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页数:11
相关论文
共 98 条
[81]  
sc, ABOUT US
[83]   Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2 [J].
Takashita, Emi ;
Kinoshita, Noriko ;
Yamayoshi, Seiya ;
Sakai-Tagawa, Yuko ;
Fujisaki, Seiichiro ;
Ito, Mutsumi ;
Iwatsuki-Horimoto, Kiyoko ;
Halfmann, Peter ;
Watanabe, Shinji ;
Maeda, Kenji ;
Imai, Masaki ;
Mitsuya, Hiroaki ;
Ohmagari, Norio ;
Takeda, Makoto ;
Hasegawa, Hideki ;
Kawaoka, Yoshihiro .
NEW ENGLAND JOURNAL OF MEDICINE, 2022, 386 (15) :1475-1477
[84]   The First Two Imported Cases of SARS-CoV-2 Omicron Variant - Tianjin Municipality, China, December 13, 2021 [J].
Tan, Zhaolin ;
Chen, Zhixiao ;
Yu, Aiping ;
Li, Xiaoyan ;
Feng, Yenan ;
Zhao, Xiang ;
Xu, Wenbo ;
Su, Xu .
CHINA CDC WEEKLY, 2022, 4 (04) :76-77
[85]   OMICRON (B.1.1.529): A new SARS-CoV-2 variant of concern mounting worldwide fear [J].
Thakur, Vikram ;
Ratho, Radha Kanta .
JOURNAL OF MEDICAL VIROLOGY, 2022, 94 (05) :1821-1824
[86]  
thehealthsite, US
[87]   The emergence and epidemic characteristics of the highly mutated SARS-CoV-2 Omicron variant [J].
Tian, Dandan ;
Sun, Yanhong ;
Xu, Huihong ;
Ye, Qing .
JOURNAL OF MEDICAL VIROLOGY, 2022, 94 (06) :2376-2383
[88]  
uclahealth, About us
[89]  
Uraki R, THERAPEUTIC EFFICACY, DOI [10.21203/rs.3.rs-1240227/v1, DOI 10.21203/RS.3.RS-1240227/V1]
[90]   Human plague: An old scourge that needs new answers [J].
Valles, Xavier ;
Stenseth, Nils Chr ;
Demeure, Christian ;
Horby, Peter ;
Mead, Paul S. ;
Cabanillas, Oswaldo ;
Ratsitorahina, Mahery ;
Rajerison, Minoarisoa ;
Andrianaivoarimanana, Voahangy ;
Ramasindrazana, Beza ;
Pizarro-Cerda, Javier ;
Scholz, Holger C. ;
Girod, Romain ;
Hinnebusch, B. Joseph ;
Vigan-Womas, Ines ;
Fontanet, Arnaud ;
Wagner, David M. ;
Telfer, Sandra ;
Yazdanpanah, Yazdan ;
Tortosa, Pablo ;
Carrara, Guia ;
Deuve, Jane ;
Belmain, Steven R. ;
D'Ortenzio, Eric ;
Baril, Laurence .
PLOS NEGLECTED TROPICAL DISEASES, 2020, 14 (08) :1-22