Hemodynamic studies of platelet thrombosis using microfluidics

被引：22
作者：
Hastings, Susan M. [1 ]
Griffin, Michael T. [1 ]
Ku, David N. [1 ]
机构：
[1] Georgia Inst Technol, GWW Sch Mech Engn, Inst Bioengn & Biosci, Atlanta, GA 30332 USA
来源：
PLATELETS | 2017年 / 28卷 / 05期
关键词：
platelets; thrombosis; microfluidics; WHOLE-BLOOD; SHEAR-STRESS; AGGREGATION; FLOW; ADHESION; COAGULATION; INHIBITOR; COLLAGEN; DEVICES; HEMOSTASIS;
D O I：
10.1080/09537104.2017.1316483
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Platelets contribute to thrombus formation in a variety of ways. Platelet adhesion, activation, and thrombus growth depend greatly on the type of hemodynamic environment surrounding an inciting event. Microfluidic systems may be used to explore these relationships. In this review, we describe some important considerations required in the design of a microfluidic system and identify some limitations that may require use of a macroscale system.
引用
收藏
页码：427 / 433
页数：7
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