Molecular cloning and sequencing of the rat interleukin-12 p40 gene

被引：0
|
作者：
Khalife, J [1 ]
Pierrot, C [1 ]
Cocude, C [1 ]
Cêtre, C [1 ]
Godin, C [1 ]
Capron, A [1 ]
机构：
[1] Inst Pasteur, INSERM, U167, Ctr Immunol & Biol Parasitaire, F-59019 Lille, France
来源：
EUROPEAN CYTOKINE NETWORK | 1998年 / 9卷 / 01期
关键词：
rat; interleukin-12; p40; promoter region; cDNA;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The nucleotide sequences containing the rat interleukin-12 p40 gene was determined. Sequencing revealed the presence of sis exons and five introns, Analysis of the 5' non-coding region showed the presence of several possible sites involved in cytokine gene regulation at the transcriptional level, Comparison of the deduced amino acid sequence of rat IL-12 p40 with that of the mouse and of human p40, showed 92% and 65% identity respectively.
引用
收藏
页码：69 / 73
页数：5
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