Synthesis and comparative lectin-binding affinity of mannosyl-coated β-cyclodextrin-dendrimer constructs

被引：84
作者：
Baussanne, I
Benito, JM
Mellet, CO
Fernández, JMG
Law, H
Defaye, J
机构：
[1] CSIC, Inst Invest Quim, E-41092 Seville, Spain
[2] CNRS, UMR 5063, F-38243 Meylan, France
[3] Univ Grenoble 1, Dept Pharmacochim Mol Glucides, F-38243 Meylan, France
[4] Univ Sevilla, Fac Quim, Dept Quim Organ, E-41071 Seville, Spain
来源：
CHEMICAL COMMUNICATIONS | 2000年 / 16期
关键词：
D O I：
10.1039/b003765f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Targeted drug delivery systems have been built from beta-cyclodextrin by monoconjugation with mannosyl-coated dendritic branches following an iterative thiourea-forming convergent strategy; the multivalent adducts showed high Concanavalin A lectin binding ability and intact inclusion capabilities.
引用
收藏
页码：1489 / 1490
页数：2
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