Membrane domains in the secretory and endocytic pathways

被引：154
作者：
Pfeffer, S [1 ]
机构：
[1] Stanford Univ, Dept Biochem, Stanford, CA 94305 USA
来源：
CELL | 2003年 / 112卷 / 04期
关键词：
D O I：
10.1016/S0092-8674(03)00118-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Progress in identifying, characterizing, and localizing the constituents,of distinct membrane bound compartments has revealed a new level of intracellular subcompartmentation. Proteins and lipids are not uniformly distributed in a given organelle, and subdomains are formed by a combination of hierarchical assembly processes and protein exclusion. Thus, functionally distinct specializations of a given organelle are physically segregated to a greater extent than previously believed.
引用
收藏
页码：507 / 517
页数：11
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