SYNTHESIS AND STRUCTURE OF VANILLIN AZOMETHINES

被引：6
|
作者：
Konstantinovic, Sandra S. [1 ]
Konstantinovic, Budimir V. [2 ]
Jovanovic, Jasmina M. [3 ]
机构：
[1] Fac Technol, Leskovac 16000, Serbia
[2] Vazduhoplovaca Bb, DOO Aura, Nish 18000, Serbia
[3] Coll Nursing, Cuprija 35000, Serbia
来源：
CHEMICAL INDUSTRY & CHEMICAL ENGINEERING QUARTERLY | 2009年 / 15卷 / 04期
关键词：
vanillin; azomethine; spectral analysis; antifungal activity; BIOLOGICAL-ACTIVITY; COMPLEXES; THIOSEMICARBAZONE; SCHIFF; CO(II); NI(II); BASES;
D O I：
10.2298/CICEQ0904279K
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Vanillin is most prominent as the principal flavor and aroma compound in vanilla Vanillin has been used as a chemical intermediate In the production of pharmaceuticals and other fine chemicals. The two intermediates, assigned as intermediates I and II, were prepared by using vanillin and 1-butylbromide or 2-chloroacetic acid respectively. The condensation of intermediates with 2,3-diaminopyridine gave azomethlnes Their structure was established by using elemental microanalysis, as well as UV/Vis, FTIR and H-1-NMR spectra. Synthesized compounds were tested for their antifungal activity against Candida albicans, Candida lipolytica and Sacharomyces cerevisiae.
引用
收藏
页码：279 / 281
页数：3
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