Relationship between 1,25-dihydroxycholecalciferol levels and functional outcome after hip fracture in elderly patients

被引:8
作者
Carpintero, Pedro
Garcia-Lazaro, Milagros
Montero, Manuel
Lopez-Castro, Pedro
Leon, Francisco
Aguilera, Critobal
机构
[1] Univ Hosp Reina Sofia, Dept Orthopaed, Cordoba 14004, Spain
[2] Univ Hosp Reina Sofia, Dept Internal Med, Cordoba 14004, Spain
[3] Univ Hosp Reina Sofia, Dept Biochem, Cordoba 14004, Spain
关键词
vitainin D; hip fracture; muscle strength; functional recovery;
D O I
10.1016/j.jbspin.2006.01.029
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A prospective study was performed in 109 patients with osteoporotic hip fracture to verify the relationship between 1,25-dihydroxycholecalciferol levels at admission and functional recovery in elderly patients with hip fracture. 47.7% of all the patients had 1,25-dihydroxycholecalciferol levels below the reference values of our laboratory. At I year of the fracture only 33 patients (30.3%) had recovered the functional level they had before the fracture. In the bivariate analysis, a statistically significant relationship was found between reduced 1,25-dihydroxycholecalciferol levels and a poorer functional recovery I year after the fracture was sustained. A multivariate analysis showed a significant relationship between 1,25-dihydroxycholecalciferol levels and absolute dependence of the patient I year after the fracture (P = 0.005; OR 6.97: CI- 1.77-27.41). (C) 2006 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:729 / 732
页数:4
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