Formation of monodisperse bubbles in a microfluidic flow-focusing device

被引：543

作者：

Garstecki, P ^{[1
]}

Gitlin, I

DiLuzio, W

Whitesides, GM

Kumacheva, E

Stone, HA

机构：

[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA

[2] Univ Toronto, Dept Chem, Toronto, ON M5S 1A1, Canada

[3] Harvard Univ, Div Engn & Appl Sci, Cambridge, MA 02138 USA

来源：

APPLIED PHYSICS LETTERS | 2004年 / 85卷 / 13期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1063/1.1796526

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

This letter describes a method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device. The bubbles can be obtained in a range of diameters from 10 to 1000 mum. The volume V-b of the bubbles scales with the flow rate q and the viscosity mu of the liquid, and the pressure p of the gas stream as V(b)proportional top/qmu. This method allows simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase. Under appropriate conditions, bubbles self-assemble into highly ordered, flowing lattices. Structures of these lattices can be adjusted dynamically by changing the flow parameters. (C) American Institute of Physics.

引用

页码：2649 / 2651

页数：3

共 25 条

[21] Interfacial tension driven monodispersed droplet formation from microfabricated channel array [J].

Sugiura, S ;

Nakajima, M ;

Iwamoto, S ;

Seki, M .

LANGMUIR, 2001, 17 (18) :5562-5566

[22] Dynamic pattern formation in a vesicle-generating microfluidic device [J].

Thorsen, T ;

Roberts, RW ;

Arnold, FH ;

Quake, SR .

PHYSICAL REVIEW LETTERS, 2001, 86 (18) :4163-4166

[23] THE MOTION OF LONG BUBBLES IN POLYGONAL CAPILLARIES .1. THIN-FILMS [J].

WONG, H ;

RADKE, CJ ;

MORRIS, S .

JOURNAL OF FLUID MECHANICS, 1995, 292 :71-94

[24] THE MOTION OF LONG BUBBLES IN POLYGONAL CAPILLARIES .2. DRAG, FLUID PRESSURE AND FLUID-FLOW [J].

WONG, H ;

RADKE, CJ ;

MORRIS, S .

JOURNAL OF FLUID MECHANICS, 1995, 292 :95-110

[25] Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets [J].

Zheng, B ;

Roach, LS ;

Ismagilov, RF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (37) :11170-11171

← 1 2 3 →