Formation of monodisperse bubbles in a microfluidic flow-focusing device

被引:543
作者
Garstecki, P [1 ]
Gitlin, I
DiLuzio, W
Whitesides, GM
Kumacheva, E
Stone, HA
机构
[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
[2] Univ Toronto, Dept Chem, Toronto, ON M5S 1A1, Canada
[3] Harvard Univ, Div Engn & Appl Sci, Cambridge, MA 02138 USA
基金
美国国家科学基金会;
关键词
D O I
10.1063/1.1796526
中图分类号
O59 [应用物理学];
学科分类号
摘要
This letter describes a method for generating monodisperse gaseous bubbles in a microfluidic flow-focusing device. The bubbles can be obtained in a range of diameters from 10 to 1000 mum. The volume V-b of the bubbles scales with the flow rate q and the viscosity mu of the liquid, and the pressure p of the gas stream as V(b)proportional top/qmu. This method allows simultaneous, independent control of the size of the individual bubbles and volume fraction of the dispersed phase. Under appropriate conditions, bubbles self-assemble into highly ordered, flowing lattices. Structures of these lattices can be adjusted dynamically by changing the flow parameters. (C) American Institute of Physics.
引用
收藏
页码:2649 / 2651
页数:3
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