Coronary calcium scoring potential of large field-of-view spectral photon-counting CT: a phantom study

被引:43
|
作者
van der Werf, Niels R. [1 ,2 ]
Si-Mohamed, S. [3 ,4 ]
Rodesch, P. A. [3 ,4 ]
van Hamersvelt, R. W. [1 ]
Greuter, M. J. W. [5 ]
Boccalini, S. [3 ,4 ]
Greffier, J. [6 ]
Leiner, T. [1 ]
Boussel, L. [3 ,4 ]
Willemink, M. J. [7 ]
Douek, P. [3 ,4 ]
机构
[1] Univ Med Ctr Utrecht, Dept Radiol, Utrecht, Netherlands
[2] Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands
[3] Hosp Civils Lyon, Louis Pradel Cardiol Hosp, Lyon, France
[4] Univ Claude Bernard Lyon 1, Univ Lyon, INSA Lyon, UJM St Etienne,CNRS,Inserm,CREATIS UMR 5220,U1206, Lyon, France
[5] Univ Groningen, Univ Med Ctr Groningen, Dept Radiol, Groningen, Netherlands
[6] Univ Montpellier, Dept Med Imaging, Med Imaging Grp, CHU Nimes, F-2415 Nimes, EA, France
[7] Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA
关键词
X-ray computed tomography; Calcium; Coronary vessels; Imaging phantoms; ARTERY CALCIUM; PULSE PILEUP; QUANTIFICATION; DISEASE; SYSTEM; RISK;
D O I
10.1007/s00330-021-08152-w
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objective The aim of the current study was, first, to assess the coronary artery calcium (CAC) scoring potential of spectral photon-counting CT (SPCCT) in comparison with computed tomography (CT) for routine clinical protocols. Second, improved CAC detection and quantification at reduced slice thickness were assessed. Methods Raw data was acquired and reconstructed with several combinations of reduced slice thickness and increasing strengths of iterative reconstruction (IR) for both CT systems with routine clinical CAC protocols for CT. Two CAC-containing cylindrical inserts, consisting of CAC of different densities and sizes, were placed in an anthropomorphic phantom. A specific CAC was detectable when 3 or more connected voxels exceeded the CAC scoring threshold of 130 Hounsfield units (HU). For all reconstructions, total CAC detectability was compared between both CT systems. Significant differences in CAC quantification (Agatston and volume scores) were assessed with Mann-Whitney U tests. Furthermore, volume scores were compared with the known CAC physical. Results CAC scores for routine clinical protocols were comparable between SPCCT and CT. SPCCT showed 34% and 4% higher detectability of CAC for the small and large phantom, respectively. At reduced slice thickness, CAC detection increased by 142% and 169% for CT and SPCCT, respectively. In comparison with CT, volume scores from SPCCT were more comparable with the physical volume of the CAC. Conclusion CAC scores using routine clinical protocols are comparable between conventional CT and SPCCT. The increased spatial resolution of SPCCT allows for increased detectability and more accurate CAC volume estimation.
引用
收藏
页码:152 / 162
页数:11
相关论文
共 50 条
  • [41] Ultra-high-resolution spectral silicon-based photon-counting detector CT for coronary CT angiography: Initial results in a dynamic phantom
    Holmes, Thomas Wesley
    Yin, Zhye
    Stevens, Grant M.
    Slavic, Scott
    Okerlund, Darin R.
    Maltz, Jonathan S.
    Pourmorteza, Amir
    JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY, 2023, 17 (05) : 341 - 344
  • [42] Quarter-millimeter spectral coronary stent imaging with photon-counting CT: Initial experience
    Symons, Rolf
    De Bruecker, Yves
    Roosen, John
    Van Camp, Laurent
    Cork, Tyler E.
    Kappler, Steffen
    Ulzheimer, Stefan
    Sandfort, Veit
    Bluemke, David A.
    Pourmorteza, Amir
    JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY, 2018, 12 (06) : 509 - 515
  • [43] Dose Reduction in Coronary Artery Calcium Scoring Using Mono-Energetic Images from Reduced Tube Voltage Dual-Source Photon-Counting CT Data: A Dynamic Phantom Study
    van der Werf, Niels R.
    van Gent, Margo
    Booij, Ronald
    Bos, Daniel
    van der Lugt, Aad
    Budde, Ricardo P. J.
    Greuter, Marcel J. W.
    van Straten, Marcel
    DIAGNOSTICS, 2021, 11 (12)
  • [44] Radiation Dose Reduction for Coronary Artery Calcium Scoring Using a Virtual Noniodine Algorithm on Photon-Counting Detector Computed-Tomography Phantom Data
    Fink, Nicola
    Zsarnoczay, Emese
    Schoepf, U. Joseph
    O'Doherty, Jim
    Griffith III, Joseph P. P.
    Pinos, Daniel
    Tesche, Christian
    Ricke, Jens
    Willemink, Martin J.
    Varga-Szemes, Akos
    Emrich, Tilman
    DIAGNOSTICS, 2023, 13 (09)
  • [45] Reproducibility of Lung Density Quantifications in Photon-counting CT: A Multi-center Phantom Study
    Sotoudeh-Paima, S.
    O'Doherty, J.
    Humphries, S. M.
    Atha, J.
    Alarab, N.
    Bache, S.
    Abadia, A.
    Ramirez-Giraldo, J.
    Estepar, R. San Jose
    Samei, E.
    Hoffman, E. A.
    Lynch, D. A.
    Fain, S. B.
    Abadi, E.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [46] Photon-Counting Detector CT Virtual Monoenergetic Images for Coronary Artery Stenosis Quantification: Phantom and In Vivo Evaluation
    Wolf, Elias V.
    Halfmann, Moritz C.
    Varga-Szemes, Akos
    Fink, Nicola
    Kloeckner, Roman
    Bockius, Stefanie
    Allmendinger, Thomas
    Hagenauer, Junia
    Koehler, Till
    Kreitner, Karl-Friedrich
    Schoepf, U. Joseph
    Muenzel, Thomas
    Dueber, Christoph
    Gori, Tommaso
    Yang, Yang
    Hell, Michaela M.
    Emrich, Tilman
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2024, 222 (03)
  • [47] Breast Tissue Characterization with Photon-counting Spectral CT Imaging: A Postmortem Breast Study
    Ding, Huanjun
    Klopfer, Michael J.
    Ducote, Justin L.
    Masaki, Fumitaro
    Molloi, Sabee
    RADIOLOGY, 2014, 272 (03) : 731 - 738
  • [48] Comparison of spectral CT imaging methods based a photon-counting detector: Experimental study
    Lee, Youngjin
    Lee, Seungwan
    Kim, Hee-Joung
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2016, 815 : 68 - 74
  • [49] Evaluation of silver sulfide nanoparticles as a contrast agent for spectral photon-counting digital mammography: a phantom study
    Lau, Kristen C.
    Hsu, Jessica C.
    Cederstrom, Bjorn
    Cormode, David P.
    Maidment, Andrew D. A.
    MEDICAL IMAGING 2019: PHYSICS OF MEDICAL IMAGING, 2019, 10948
  • [50] Ultra-High-Resolution and K-Edge Imaging of Prosthetic Heart Valves With Spectral Photon-Counting CT A Phantom Study
    Boccalini, Sara
    Mayard, Charles
    Lacombe, Hugo
    Villien, Marjorie
    Si-Mohamed, Salim
    Delahaye, Francois
    Boussel, Loic
    Budde, Ricardo P. J.
    Pozzi, Matteo
    Douek, Philippe
    INVESTIGATIVE RADIOLOGY, 2024, 59 (08) : 589 - 598