Coronary calcium scoring potential of large field-of-view spectral photon-counting CT: a phantom study

被引:43
|
作者
van der Werf, Niels R. [1 ,2 ]
Si-Mohamed, S. [3 ,4 ]
Rodesch, P. A. [3 ,4 ]
van Hamersvelt, R. W. [1 ]
Greuter, M. J. W. [5 ]
Boccalini, S. [3 ,4 ]
Greffier, J. [6 ]
Leiner, T. [1 ]
Boussel, L. [3 ,4 ]
Willemink, M. J. [7 ]
Douek, P. [3 ,4 ]
机构
[1] Univ Med Ctr Utrecht, Dept Radiol, Utrecht, Netherlands
[2] Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands
[3] Hosp Civils Lyon, Louis Pradel Cardiol Hosp, Lyon, France
[4] Univ Claude Bernard Lyon 1, Univ Lyon, INSA Lyon, UJM St Etienne,CNRS,Inserm,CREATIS UMR 5220,U1206, Lyon, France
[5] Univ Groningen, Univ Med Ctr Groningen, Dept Radiol, Groningen, Netherlands
[6] Univ Montpellier, Dept Med Imaging, Med Imaging Grp, CHU Nimes, F-2415 Nimes, EA, France
[7] Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA
关键词
X-ray computed tomography; Calcium; Coronary vessels; Imaging phantoms; ARTERY CALCIUM; PULSE PILEUP; QUANTIFICATION; DISEASE; SYSTEM; RISK;
D O I
10.1007/s00330-021-08152-w
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objective The aim of the current study was, first, to assess the coronary artery calcium (CAC) scoring potential of spectral photon-counting CT (SPCCT) in comparison with computed tomography (CT) for routine clinical protocols. Second, improved CAC detection and quantification at reduced slice thickness were assessed. Methods Raw data was acquired and reconstructed with several combinations of reduced slice thickness and increasing strengths of iterative reconstruction (IR) for both CT systems with routine clinical CAC protocols for CT. Two CAC-containing cylindrical inserts, consisting of CAC of different densities and sizes, were placed in an anthropomorphic phantom. A specific CAC was detectable when 3 or more connected voxels exceeded the CAC scoring threshold of 130 Hounsfield units (HU). For all reconstructions, total CAC detectability was compared between both CT systems. Significant differences in CAC quantification (Agatston and volume scores) were assessed with Mann-Whitney U tests. Furthermore, volume scores were compared with the known CAC physical. Results CAC scores for routine clinical protocols were comparable between SPCCT and CT. SPCCT showed 34% and 4% higher detectability of CAC for the small and large phantom, respectively. At reduced slice thickness, CAC detection increased by 142% and 169% for CT and SPCCT, respectively. In comparison with CT, volume scores from SPCCT were more comparable with the physical volume of the CAC. Conclusion CAC scores using routine clinical protocols are comparable between conventional CT and SPCCT. The increased spatial resolution of SPCCT allows for increased detectability and more accurate CAC volume estimation.
引用
收藏
页码:152 / 162
页数:11
相关论文
共 50 条
  • [21] High Resolution, Full Field-of-View, Whole Body Photon-Counting Detector CT: System Assessment and Initial Experience
    Rajendran, Kishore
    Marsh, Jeffrey
    Petersilka, Martin
    Henning, Andre
    Shanblatt, Elisabeth
    Schmidt, Bernhard
    Flohr, Thomas
    Fletcher, Joel
    McCollough, Cynthia
    Leng, Shuai
    MEDICAL IMAGING 2021: PHYSICS OF MEDICAL IMAGING, 2021, 11595
  • [22] Full field-of-view, high-resolution, photon-counting detector CT: technical assessment and initial patient experience
    Rajendran, Kishore
    Petersilka, Martin
    Henning, Andre
    Shanblatt, Elisabeth
    Marsh, Jeffrey, Jr.
    Thorne, Jamison
    Schmidt, Bernhard
    Flohr, Thomas
    Fletcher, Joel
    McCollough, Cynthia
    Leng, Shuai
    PHYSICS IN MEDICINE AND BIOLOGY, 2021, 66 (20):
  • [23] Effect of temporal resolution on calcium scoring: insights from photon-counting detector CT
    Sartoretti, Thomas
    Mergen, Victor
    Dzaferi, Amina
    Allmendinger, Thomas
    Manka, Robert
    Alkadhi, Hatem
    Eberhard, Matthias
    INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 2025, 41 (03): : 615 - 625
  • [24] Tube voltage-independent coronary calcium scoring on a first-generation dual-source photon-counting CT-a proof-of-principle phantom study
    Mergen, V
    Higashigaito, K.
    Allmendinger, T.
    Manka, R.
    Euler, A.
    Alkadhi, H.
    Eberhard, M.
    INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 2022, 38 (04): : 905 - 912
  • [25] Quantification accuracy in photon-counting detector CT for coronary artery calcium score: a pilot study
    Wang, Mengzhen
    Zhang, Xu
    Li, Jiqang
    Dong, Haipeng
    Xu, Zhihan
    Yan, Fuhua
    Yang, Wenjie
    INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 2024, 40 (10): : 2181 - 2191
  • [26] Iodine Quantification in a Full Field-Of-View Photon-Counting-Detector CT
    Rajendran, K.
    Marsh, J.
    Thorne, J.
    Shanblatt, E.
    Fletcher, J.
    McCollough, C.
    Leng, S.
    MEDICAL PHYSICS, 2021, 48 (06)
  • [27] 3D-Printed Anthropomorphic Phantom Framework for Spectral Photon-Counting CT: A Breast Phantom Application
    Katsikari, Kyriaki
    Francis, Nadine
    Maalej, Nabil
    Pitsalidis, Charalampos
    Raja, Aamir Younis
    IEEE ACCESS, 2025, 13 : 6397 - 6412
  • [28] Photon-counting computed tomography of coronary and peripheral artery stents: a phantom study
    Thomas Stein
    Jana Taron
    Niklas Verloh
    Michael Doppler
    Alexander Rau
    Muhammad Taha Hagar
    Sebastian Faby
    Dimos Baltas
    Dirk Westermann
    Isabelle Ayx
    Stefan O. Schönberg
    Konstantin Nikolaou
    Christopher L. Schlett
    Fabian Bamberg
    Jakob Weiss
    Scientific Reports, 13
  • [29] Photon-counting computed tomography of coronary and peripheral artery stents: a phantom study
    Stein, Thomas
    Taron, Jana
    Verloh, Niklas
    Doppler, Michael
    Rau, Alexander
    Hagar, Muhammad Taha
    Faby, Sebastian
    Baltas, Dimos
    Westermann, Dirk
    Ayx, Isabelle
    Schoenberg, Stefan O.
    Nikolaou, Konstantin
    Schlett, Christopher L.
    Bamberg, Fabian
    Weiss, Jakob
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [30] Discrimination Between Calcium Hydroxyapatite and Calcium Oxalate Using Multienergy Spectral Photon-Counting CT
    Kirkbride, Tracy E.
    Raja, Aamir Y.
    Mueller, Kristin
    Bateman, Christopher J.
    Becce, Fabio
    Anderson, Nigel G.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2017, 209 (05) : 1088 - 1092