The impact of genomics on public health practice

被引:14
作者
Burton, H. [1 ]
Jackson, C. [2 ]
Abubakar, I. [2 ,3 ]
机构
[1] PHG Fdn, Cambridge CB1 8RN, England
[2] UCL, Ctr Infect Dis Epidemiol, Mortimer Market Ctr, London WC1E 6JB, England
[3] Publ Hlth England, Ctr Infect Dis Surveillance & Control, London NW9 5EQ, England
关键词
genetics; genomics; screening; health protection; personalized prevention; developing world; public health; TUBERCULOSIS; DISEASE; TRANSMISSION; MUTATIONS; EVOLUTION; MEDICINE;
D O I
10.1093/bmb/ldu032
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Genomic science is developing rapidly, and engagement of public health professionals will be necessary to appraise new technologies and use them effectively. We use established domains of public health and draw on the literature and expert knowledge to illustrate how genomic technologies give rise to new applications. Genomic technologies are useful in rare inherited disease, including population screening programmes, in health care and for surveillance, diagnosis and treatment of infectious disease. It is less clear when and how genetic susceptibility testing will be used for common chronic disease prevention or protection from environmental hazards. Developments in public health practice will be necessary to ensure rapid and effective implementation of genomic science. Public health researchers should address how to accelerate the implementation of genomics for health benefit in developed and developing countries.
引用
收藏
页码:37 / 46
页数:10
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