Kolokosides A-D:: Triterpenoid glycosides from a Hawaiian isolate of Xylaria sp.

被引：49

作者：

Deyrup, Stephen T.

Gloer, James B. ^{[1
]}

O'Donnell, Kerry

Wicklow, Donald T.

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

[2] USDA ARS, Natl Ctr Agr Utilizat Res, Mycotoxin Res Unit, Peoria, IL 61604 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 03期

关键词：

D O I：

10.1021/np060546k

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new triterpenoid glycosides, kolokosides A-D (1-4), along with the known compound 19,20-epoxycytochalasin N, were isolated from cultures of a Hawaiian wood-decay fungus (Xylaria sp.). The structures and relative configurations of 1-4 were determined primarily by analysis of NMR data, and the absolute configuration of 1 was assigned by application of the exciton chirality method. Compound 1 exhibited activity against Gram-positive bacteria.

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页码：378 / 382

页数：5

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