Factors associated with the risk of COVID-19 in health-care workers

Background: Although healthcare personnel are considered a high-risk group for SARS-CoV-2 infection due to their exposure, research on the factors associated with their infection is limited. The objec-tive was to identify factors associated with the acquisition of COVID-19 in healthcare personnel. Methods: a multicenter, cross-sectional study with nested cases and controls was carried out in 23 hospitals in Argentina. A structured survey was used to collect demographic, institutional and behavioral variables from healthcare personnel with positive RT-PCR for SARS-CoV2 (cases) and healthcare personnel with negative test results (controls). Those variables significantly associated with the condition of having had COVID-19 in the bivariate analysis were included in a multivariate analysis. Results: A total of 2088 workers participated in the study, with an incidence of 1.41 cases per 10 000 worker-hours (95%CI 1.35-1.48). Being male, (OR 1.60; 95%CI 1.32-1.95), working in social security, (OR 1.53; 95%CI 1.13-2.07), being nursing staff, (OR 1.46; 95%CI 1.22-1.74), having personal protective equipment, (OR 0.33; 95%CI 0.18-0.62), sharing unprotected common spaces with other workers, (OR 1.98; 95%CI 1. 60-2.44), living with people confirmed or suspected of COVID-19 (OR 1.69; 95%CI 1.37-2.09), sharing infusions or other drinks and/or food with people in the community (OR 1.31; 95%CI 1.02-1.70), feeling distressed (OR 1.85; 95%CI 1.55-2.21) and were independently associated with the risk of acquiring COVID-19. Discussion: This study allowed us to identify different potentially modifiable fac-tors on which action should be taken to reduce the risk of acquiring COVID-19 by the healthcare personnel.