Biological underpinnings of psychogenic nonepileptic seizures: directions for future research

被引：16

作者：

Asadi-Pooya, Ali A. ^{[1
,2
]}

机构：

[1] Thomas Jefferson Univ, Dept Neurol, Jefferson Comprehens Epilepsy Ctr, Philadelphia, PA 19107 USA

[2] Shiraz Univ Med Sci, Shiraz Med Sch, Neurosci Res Ctr, Shiraz, Iran

来源：

NEUROLOGICAL SCIENCES | 2016年 / 37卷 / 07期

关键词：

Brain; Connectivity; Etiology; Genetics; Nonepileptic seizures; FUNCTIONAL CONNECTIVITY; GUT MICROBIOTA; CHILDHOOD MALTREATMENT; NEUROTROPHIC FACTOR; CORTICAL THICKNESS; BRAIN CONNECTIVITY; GENETICS; DEPRESSION; NETWORKS; EPILEPSY;

D O I：

10.1007/s10072-016-2540-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Psychogenic nonepileptic seizures (PNES) are relatively common occurrences in epilepsy centers, but their pathophysiology is still poorly understood. Research that elucidates the pathophysiology of PNES, including their neurobiological basis and biomarkers, may have important clinical implications. The literature provides some evidence that genetic factors, intrinsic factors, and environmental factors probably play a significant role as the biological underpinnings of PNES. Researchers may be able to learn more about the pathophysiology of PNES by investigating the effects of each of these factors on functional and structural brain connectivity.

引用

页码：1033 / 1038

页数：6

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