Calcium metabolism of pregnant rats fed a vitamin D-depleted diet

被引：3
|
作者：
Yamagishi, Norio
Sassa, Hiromi
Sato, Reeko
Taniguchi, Kazuyuki
Okura, Norimoto
Sato, Shigeru
Naito, Yoshihisa [1 ]
机构：
[1] Iwate Univ, Fac Agr, Dept Clin Vet Med, Morioka, Iwate 0208550, Japan
[2] Iwate Univ, Fac Agr, Dept Vet Basic Sci, Morioka, Iwate 0208550, Japan
[3] Kamikawa Chuo Agr Mutual Aid Assoc, Cent Vet Clin Ctr, Asahikawa, Hokkaido 0788208, Japan
[4] Miyagi Prefectural Federated Agr Mutual Aid Assoc, Kenan Vet Clin Ctr, Shiroishi, Miyagi 9890731, Japan
来源：
JOURNAL OF VETERINARY MEDICAL SCIENCE | 2007年 / 69卷 / 04期
关键词：
D O I：
10.1292/jvms.69.441
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The effects of vitamin D (VD) deficiency on calcium (Ca) metabolism during pregnancy were evaluated in rats fed VD-repleted (VD-repleted rats) and VD-depleted (VD-depleted rats) diets. In the VD-depleted rats, the plasma concentrations of 1,25-dihydroxyvitamin D and Ca decreased severely, whereas the parathyroid hormone concentrations increased. The Ca contents of the feces of the VD-depleted rats were higher than those of the VD-repleted rats. The fetal Ca contents of the VD-repleted and VD-depleted rats increased continuously, but that of the VD-depleted rats was lower. These data reveal that VD deficiency during pregnancy induces severe hypocalcemia due to reduced intestinal absorption of Ca and elevated fetal demand for Ca.
引用
收藏
页码：441 / 443
页数：3
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