Calcium metabolism of pregnant rats fed a vitamin D-depleted diet

被引：3

作者：

Yamagishi, Norio

Sassa, Hiromi

Sato, Reeko

Taniguchi, Kazuyuki

Okura, Norimoto

Sato, Shigeru

Naito, Yoshihisa ^{[1
]}

机构：

[1] Iwate Univ, Fac Agr, Dept Clin Vet Med, Morioka, Iwate 0208550, Japan

[2] Iwate Univ, Fac Agr, Dept Vet Basic Sci, Morioka, Iwate 0208550, Japan

[3] Kamikawa Chuo Agr Mutual Aid Assoc, Cent Vet Clin Ctr, Asahikawa, Hokkaido 0788208, Japan

[4] Miyagi Prefectural Federated Agr Mutual Aid Assoc, Kenan Vet Clin Ctr, Shiroishi, Miyagi 9890731, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2007年 / 69卷 / 04期

关键词：

D O I：

10.1292/jvms.69.441

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The effects of vitamin D (VD) deficiency on calcium (Ca) metabolism during pregnancy were evaluated in rats fed VD-repleted (VD-repleted rats) and VD-depleted (VD-depleted rats) diets. In the VD-depleted rats, the plasma concentrations of 1,25-dihydroxyvitamin D and Ca decreased severely, whereas the parathyroid hormone concentrations increased. The Ca contents of the feces of the VD-depleted rats were higher than those of the VD-repleted rats. The fetal Ca contents of the VD-repleted and VD-depleted rats increased continuously, but that of the VD-depleted rats was lower. These data reveal that VD deficiency during pregnancy induces severe hypocalcemia due to reduced intestinal absorption of Ca and elevated fetal demand for Ca.

引用

页码：441 / 443

页数：3

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