Calcium metabolism of pregnant rats fed a vitamin D-depleted diet

被引：3
|
作者：
Yamagishi, Norio
Sassa, Hiromi
Sato, Reeko
Taniguchi, Kazuyuki
Okura, Norimoto
Sato, Shigeru
Naito, Yoshihisa [1 ]
机构：
[1] Iwate Univ, Fac Agr, Dept Clin Vet Med, Morioka, Iwate 0208550, Japan
[2] Iwate Univ, Fac Agr, Dept Vet Basic Sci, Morioka, Iwate 0208550, Japan
[3] Kamikawa Chuo Agr Mutual Aid Assoc, Cent Vet Clin Ctr, Asahikawa, Hokkaido 0788208, Japan
[4] Miyagi Prefectural Federated Agr Mutual Aid Assoc, Kenan Vet Clin Ctr, Shiroishi, Miyagi 9890731, Japan
来源：
JOURNAL OF VETERINARY MEDICAL SCIENCE | 2007年 / 69卷 / 04期
关键词：
D O I：
10.1292/jvms.69.441
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The effects of vitamin D (VD) deficiency on calcium (Ca) metabolism during pregnancy were evaluated in rats fed VD-repleted (VD-repleted rats) and VD-depleted (VD-depleted rats) diets. In the VD-depleted rats, the plasma concentrations of 1,25-dihydroxyvitamin D and Ca decreased severely, whereas the parathyroid hormone concentrations increased. The Ca contents of the feces of the VD-depleted rats were higher than those of the VD-repleted rats. The fetal Ca contents of the VD-repleted and VD-depleted rats increased continuously, but that of the VD-depleted rats was lower. These data reveal that VD deficiency during pregnancy induces severe hypocalcemia due to reduced intestinal absorption of Ca and elevated fetal demand for Ca.
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页码：441 / 443
页数：3
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