SYNTHESIS OF SUBSTITUTED TETRAARYL IMIDAZOLES ON A SOLID SUPPORT UNDER SOLVENT FREE CONDITIONS

被引：0
|
作者：
Sharma, Gyanendra Kumar [1 ]
Sain, Ashok [1 ]
Kumar, Nitin [1 ]
Pathak, Devender [1 ]
机构：
[1] Rajiv Acad Pharm, Dept Pharmaceut Chem, Mathura 281001, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2010年 / 19卷 / 03期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Using silica gel as solid support tetraaryl imidazoles (2a-h) have been synthesized and characterized by FTIR, H-1 NMR, Mass spectroscopy and elemental analysis. These compounds were screened for antibacterial activity against S. aureus, B. subtilis, E. coli, P aeruginosa, K. pneumoniae and short term anticancer activity against Ehrlich's Ascites Carcinoma (EAC) cell lines.
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页码：311 / 312
页数：2
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