Prognostic Utility of Clinical Epilepsy Severity Score Versus Pretreatment Hypsarrhythmia Scoring in Children With West Syndrome

被引：8

作者：

Sehgal, Rachna ^{[1
,2
]}

Gulati, Sheffali ^{[1
]}

Sapra, Savita ^{[1
]}

Tripathi, Manjari ^{[3
]}

Pandey, Ravinder Mohan ^{[4
]}

Kabra, Madhulika ^{[1
]}

机构：

[1] All India Inst Med Sci, Dept Pediat, New Delhi, India

[2] Vardhmaan Mahavir Med Coll & Safdarjang Hosp, Dept Pediat, New Delhi, India

[3] All India Inst Med Sci, Dept Neurol, New Delhi, India

[4] All India Inst Med Sci, Dept Biostat, New Delhi, India

来源：

CLINICAL EEG AND NEUROSCIENCE | 2017年 / 48卷 / 04期

关键词：

West syndrome; outcomes; neurodevelopment; epilepsy; motor; Kramer Global Score; E-Chess; INFANTILE SPASMS; ELECTROENCEPHALOGRAPHIC FINDINGS; PATTERNS; EEG; COHORT; SCALE;

D O I：

10.1177/1550059416662425

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This cross-sectional study assessed the impact of clinical epilepsy severity and pretreatment hypsarrhythmia severity on epilepsy and cognitive outcomes in treated children with West syndrome. Thirty-three children, aged 1 to 5 years, with infantile spasms were enrolled if pretreatment EEG records were available, after completion of 1 year of onset of spasms. Neurodevelopment was assessed by Development Profile 3 and Gross Motor Function Classification System. Epilepsy severity in the past 1 year was determined by the Early Childhood Epilepsy Severity Score (E-Chess). Kramer Global Score of hypsarrhythmia severity was computed. Kramer Global Score (8) and E-Chess (9) in the past 1 year were associated with favorable epilepsy outcome but not neurodevelopmental or motor outcome.

引用

页码：280 / 287

页数：8

共 2 条

[1] Prognostic utility of hypsarrhythmia scoring in children with West syndrome after ketogenic diet [J].

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CLINICAL NEUROLOGY AND NEUROSURGERY, 2019, 184

[2] The Efficacy of Moderate-to-High Dose Oral Prednisolone Versus Low-to-Moderate Dose Intramuscular Corticotropin for Improvement of Hypsarrhythmia in West Syndrome: A Randomized, Single-Blind, Parallel Clinical Trial [J].

Wanigasinghe, Jithangi ;

Arambepola, Carukshi ;

Ranganathan, Shalini Sri ;

Sumanasena, Samanmali ;

Muhandiram, Eindrini C. .

PEDIATRIC NEUROLOGY, 2014, 51 (01) :24-30

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