High efficient iron-catalyzed transfer hydrogenation of quinolines with Hantzsch ester as hydrogen source under mild conditions

被引：27

作者：

He, Renke ^{[1
]}

Cui, Peng ^{[1
]}

Pi, Danwei ^{[1
]}

Sun, Yan ^{[1
]}

Zhou, Haifeng ^{[1
]}

机构：

[1] China Three Gorges Univ, Coll Biol & Pharmaceut Sci, Hubei Key Lab Nat Prod Res & Dev, Yichang 443002, Peoples R China

来源：

TETRAHEDRON LETTERS | 2017年 / 58卷 / 36期

基金：

中国国家自然科学基金;

关键词：

Iron catalysis; Transfer hydrogenation; Quinolines; Hantzsch ester; ASYMMETRIC TRANSFER HYDROGENATION; ENANTIOSELECTIVE REDUCTION; BRONSTED ACID; C(SP(3))-H FUNCTIONALIZATION; ORGANIC-SYNTHESIS; METHYL AZAARENES; HETEROCYCLES; ISOQUINOLINE; DERIVATIVES; TETRAHYDROQUINOLINES;

D O I：

10.1016/j.tetlet.2017.07.101

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly efficient transfer hydrogenation of quinolines with Hantzsch ester as hydrogen source in the presence of 1 mol% Fe(OTf)(2) under mild conditions has been developed. A series of substituted 1,2,3,4-tetrahydroquinoline derivatives were afforded in excellent yields with good functional group tolerance. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：3571 / 3573

页数：3

共 53 条

[1] COBALT STEARATE ALUMINUM ALKYL CATALYZED HYDROGENATION OF SUBSTITUTED QUINOLINES, ISOQUINOLINE AND NAPHTHALENE [J].