Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Cirrhosis Confirmed by Liver Histology after 14 Years

被引：0

作者：

Kawanaka, Miwa ^{[1
]}

Nishino, Ken ^{[1
]}

Morimoto, Yumiko ^{[1
]}

Ishii, Katsunori ^{[1
]}

Tanikawa, Tomohiro ^{[1
]}

Urata, Noriyo ^{[1
]}

Suehiro, Mitsuhiko ^{[1
]}

Sasai, Takako ^{[1
]}

Haruma, Ken ^{[1
]}

Kawamoto, Hirofumi ^{[1
]}

机构：

[1] Kawasaki Med Sch, Kawasaki Med Ctr, Dept Gen Internal Med 2, Okayama, Japan

来源：

INTERNAL MEDICINE | 2021年 / 60卷 / 09期

关键词：

biopsy; histology; nonalcoholic fatty liver disease; nonalcoholic steatohepatitis; cirrhosis; TERM-FOLLOW-UP; FIBROSIS PROGRESSION; DISEASE; STEATOSIS;

D O I：

10.2169/internalmedicine.6118-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 44-year-old patient progressed from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH) cirrhosis. She was diagnosed with NAFL via a liver biopsy. At 56 years old, she was diagnosed with NASH stage 3 via a second liver biopsy. One year later, she was diagnosed with NASH cirrhosis via a third liver biopsy. This is the first study to report the gradual deterioration of liver histology shown via three liver biopsies and fibrosis markers in a patient who progressed from NAFL to NASH cirrhosis. Following menopause, it is necessary to be aware of the rapid development of liver fibrosis.

引用

页码：1397 / 1401

页数：5

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