Brazilian Protocol for Sexually Transmitted Infections 2020: syphilis diagnostic tests

被引：9

作者：

Gaspar, Pamela Cristina ^{[1
,2
]}

Bigolin, Alisson ^{[1
,3
]}

Alonso Neto, Jose Boullosa ^{[1
]}

dos Santos Pereira, Esdras Daniel ^{[1
]}

Bazzo, Maria Luiza ^{[3
]}

机构：

[1] Minist Saude Brasil, Dept Doencas Condicoes Cron & Infeccoes Sexualmen, Secretaria Vigilancia Saude, Brasilia, DF, Brazil

[2] Univ Brasilia, Programa Posgrad Saude Colet, Brasilia, DF, Brazil

[3] Univ Fed Santa Catarina, Lab Biol Mol Microbiol & Sorol, Florianopolis, SC, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2021年 / 54卷

关键词：

Syphilis; Neurosyphilis; Congenital syphilis; Diagnosis; CEREBROSPINAL-FLUID;

D O I：

10.1590/0037-8682-630-2020

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The recommendations for diagnostic tests for investigating syphilis are part of the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections and the Technical Manual for Syphilis Diagnosis, published by the Brazilian Ministry of Health. These recommendations were developed based on scientific evidence and discussions with a panel of experts. This article presents direct tests to detect Treponema pallidum in lesions and algorithms that combine treponemal and nontreponemal antibody tests to assist in syphilis diagnosis, with the aim of contributing to the efforts of health service managers and health professionals in qualifying health care. The article also covers the use of non-treponemal tests to investigate neurosyphilis and guidelines for interpreting non-treponemal antibody titers in monitoring the treatment and diagnosis of congenital syphilis, as well as prospects for innovations in diagnosis. The critical role of rapid immunochromatographic treponemal tests for public health and for addressing syphilis is also highlighted.

引用

页数：8

共 42 条

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