Amantadine-Induced Livedo Racemosa

被引:3
作者
Criado, Paulo Ricardo [1 ]
Alavi, Afsaneh [2 ]
Valente, Neusa Yuriko Sakai [1 ]
Sotto, Mirian Nacagami [1 ]
机构
[1] Univ Sao Paulo, Sao Paulo, Brazil
[2] Univ Toronto, Toronto, ON, Canada
关键词
amantadine; livedo reticularis; livedo racemosa; livedo; vasculopathy; RETICULARIS;
D O I
10.1177/1534734615603566
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Although livedo reticularis is a known adverse effect of amantadine, only limited studies have addressed this association. Livedo racemosa in contrast to livedo reticularis is characterized by a striking violaceous netlike pattern of the skin similar to livedo reticularis with a different histopathology and morphology (irregular, broken circular segments). In this case report, we present 2 cases of livedo racemosa and edema of lower extremities following amantadine treatment. The cutaneous biopsies in both cases showed intraluminal thrombi in subcutaneous blood vessels without evidence of vasculitis, which is consistent with livedo racemosa.
引用
收藏
页码:78 / 81
页数:4
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