Amyloid Cardiomyopathy Disease on the Rise

被引:18
作者
Liao, Ronglih
Ward, Jennifer E.
机构
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Genet, Boston, MA USA
[2] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Cardiovasc Med, Boston, MA USA
关键词
aging; amyloid; gadolinium; heart failure; mutation; SENILE SYSTEMIC AMYLOIDOSIS; ALZHEIMERS-DISEASE; TRANSTHYRETIN; MODEL; MICE;
D O I
10.1161/CIRCRESAHA.117.310643
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Amyloidoses represent a group of human degenerative diseases characterized by the deposition of aggregates of abnormally folded proteins in single or multi-organs. Whereas neurological amyloidoses, such as Alzheimer and Parkinson disease, have received the greatest recognition, there also exists many systemic amyloidoses that affect many target organs, including the heart.
引用
收藏
页码:1865 / 1867
页数:3
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