Synthesis of guanidine derivatives and molecular recognition

被引:6
作者
Qi, YX [1 ]
Gao, HX [1 ]
Yang, M [1 ]
Xia, CG [1 ]
Suo, J [1 ]
机构
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo SYntheis & Select Oxidat, Lanzhou 730000, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1081/SCC-120017128
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Five Guanidine Derivatives bearing acyl group were synthesized by the reaction of acyl chloride with 1,1,3,3-tetramethylguanidine. Their structures were confirmed by IR, H-1-NMR, EI-MS, HRMS and elementary analysis. One of them (4a) was also characterized by X-ray. Preliminary results of interaction with phosphate-containing biomolecules and adipate showed that all of them exhibited the abilities of molecular recognition.
引用
收藏
页码:1073 / 1079
页数:7
相关论文
共 50 条
[31]   A METHOD FOR THE DESULFURIZATION OF SUBSTITUTED THIOUREAS APPLIED TO THE SYNTHESIS OF TETRAZOLE AND GUANIDINE DERIVATIVES [J].
Parvathi, Edalada Venkata Krishna ;
Pinapati, Srinivasa Rao ;
Tamminana, Ramana ;
Rudraraju, Ramesh Raju .
HETEROCYCLIC LETTERS, 2023, 13 (03) :591-601
[32]   Features of Synthesis and Antimicrobial Properties of Guanidine-Containing Carboxymethylcellulose Derivatives [J].
Akhmedov, O. R. ;
Shomurotov, Sh. A. ;
Turaev, A. S. .
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2022, 48 (07) :1379-1386
[33]   Features of Synthesis and Antimicrobial Properties of Guanidine-Containing Carboxymethylcellulose Derivatives [J].
O. R. Akhmedov ;
Sh. A. Shomurotov ;
A. S. Turaev .
Russian Journal of Bioorganic Chemistry, 2022, 48 :1379-1386
[34]   Molecular Recognition Studies on Naphthyridine Derivatives [J].
Carlos Iglesias-Sanchez, Jose ;
Santa Maria, Dolores ;
Claramunt, Rosa M. ;
Elguero, Jose .
MOLECULES, 2010, 15 (03) :1213-1222
[35]   Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives [J].
Hong, Liang ;
Kim, Iris H. ;
Tombola, Francesco .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (27) :9971-9976
[36]   SYNTHESIS OF GUANIDINE [J].
TITOVA, KV ;
KOLMAKOVA, EI ;
ROSOLOVSKII, VY .
BULLETIN OF THE ACADEMY OF SCIENCES OF THE USSR DIVISION OF CHEMICAL SCIENCE, 1979, 28 (12) :2616-2617
[37]   GUANIDINE DERIVATIVES OF NITROGEN HETEROCYCLES [J].
PORTNYAG.VA ;
DANILENK.VF ;
DENISOV, ND ;
VINNIKOV.AV .
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1971, (02) :249-&
[38]   Synthesis of novel β-cyclodextrin and calixarene derivatives and their use in gas sensing on the basis of molecular recognition [J].
Liu, Y ;
You, CC ;
Kang, SZ ;
Wang, C ;
Chen, F ;
He, XW .
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2002, 2002 (04) :607-613
[39]   STRUCTURES OF 2 GUANIDINE DERIVATIVES [J].
CARPENTER, GB ;
EVERS, R .
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1990, 46 :2175-2177
[40]   SOME GUANIDINE AND DIGUANIDE DERIVATIVES [J].
ROYER, R .
JOURNAL OF THE CHEMICAL SOCIETY, 1949, (JUN) :1665-1666