Tumor-like Lesions in Patients with Granulomatosis with Polyangiitis: A Case Series

Background: Granulomatosis with potyangiitis (GPA) is a rare small vessel vascutitis. It usually involves the respiratory tract and kidneys. Rarely, tumor-resembling inflammatory changes ensue. Objectives: To report three unique cases of GPA presenting with tumor-like lesions in various organs. Methods: We presented three cases of GPA. Case 1 presented with typical upper respiratory symptoms of GPA and a mediastinal mass. Case 2 presented with low back pain, a large retroperitoneat mass, and nodular skin lesions. Case 3 presented with epigastric pain and a paravertebral inflammatory mass. Results: The patients were treated successfully with rituximab. Conclusions: Clinicians should be aware of this presentation of granulomatosis with polyangiitis, which is known as Tumefaction Wegener's granulomatosis.