Liquid chromatography-tandem mass spectrometry for the determination of chrysoidine in yellow-fin tuna

被引：25
作者：
Gui, Wenjun [1 ]
Xu, Yong [2 ]
Shou, Linfei [2 ]
Zhu, Guonian [1 ]
Ren, Yiping [3 ]
机构：
[1] Zhejiang Univ, Inst Pesticide & Environm Toxicol, Hangzhou 310029, Zhejiang, Peoples R China
[2] Inst Control Agrochem, Hangzhou 310029, Zhejiang, Peoples R China
[3] Zhejiang Prov Ctr Dis Prevent & Control, Chem & Phys Lab, Hangzhou 310009, Zhejiang, Peoples R China
来源：
FOOD CHEMISTRY | 2010年 / 122卷 / 04期
关键词：
Liquid chromatography-tandem mass spectrometry; Chrysoidine; Yellow-fin tuna; Solid phase extraction; FOOD;
D O I：
10.1016/j.foodchem.2010.02.054
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A high performance liquid chromatography (HPLC) coupled to electrospray ionisation tandem mass spectrometry (MS/MS) method was described for the residue detection of chrysoidine in yellow-fin tuna in the present study. Samples were cleaned up with solid phase extraction (SPE) cartridge, and then injected into HPLC for separation. Multiple-reaction monitoring (MRM) was applied for quantitative determination. Results showed that the low limit of detection (LOD) of the method was 1.25 x 10(-12) g, and the low limit of quantification (LOQ) was 0.42 mu g/L. The standard calibration curve was y = 2333.9x -845 (r(2) > 0.99) with the linear range of 0.63-100 mu g/L. The average recoveries of chrysoidine ranged from 86.0% to 108.0% when the spiked concentration was from 0.5 mu g/kg to 201 mu g/kg. And the developed method also showed the good test precisions (RSD%: 4.38-14.27%). (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1230 / 1234
页数：5
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