The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore

被引:192
作者
Lin, Jinshui [1 ,2 ]
Cheng, Juanli [1 ,2 ]
Wang, Yao [3 ,4 ]
Shen, Xihui [3 ,4 ]
机构
[1] Yanan Univ, Shaanxi Engn & Technol Res Ctr Conservat & Utiliz, Yanan, Peoples R China
[2] Yanan Univ, Coll Life Sci, Yanan, Peoples R China
[3] Northwest A&F Univ, Coll Life Sci, Shaanxi Key Lab Agr & Environm Microbiol, Yangling, Shaanxi, Peoples R China
[4] Northwest A&F Univ, State Key Lab Crop Stress Biol Arid Areas, Yangling, Shaanxi, Peoples R China
基金
中国国家自然科学基金;
关键词
Pseudomonas aeruginosa; PQS; quorum sensing; iron acquisition; cytotoxicity; outer-membrane vesicles; immune regulation; MEMBRANE-VESICLE PRODUCTION; TO-CELL COMMUNICATION; AERUGINOSA PAO1; VIRULENCE FACTORS; BACTERIAL-CELL; MOLECULES; GENES; MECHANISM; PROTEINS; PATHWAY;
D O I
10.3389/fcimb.2018.00230
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The Pseudomonas quinolone signal (PQS) has been studied primarily in the context of its role as a quorum-sensing signaling molecule. Recent data suggest, however, that this molecule may also function to mediate iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, or to exert host immune modulatory activities.
引用
收藏
页数:9
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