Oxidation of olefins by palladium(II) Part 17. An asymmetric chlorohydrin synthesis catalyzed by a bimetallic palladium(II) complex

被引：43
作者：
El-Qisairi, A [1 ]
Henry, PM [1 ]
机构：
[1] Loyola Univ, Dept Chem, Chicago, IL 60626 USA
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2000年 / 603卷 / 01期
关键词：
palladium(II); catalysis; asymmetric; olefins; chlorohydrins;
D O I：
10.1016/S0022-328X(00)00070-X
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Previous studies showed that oxidation of cl-olefins with monometallic catalysts containing chiral diphosphines and diamines gave chlorohydrins with poor to good enantioselectivites (28-82% ee). The present studies demonstrate that bimetallic catalysts containing a beta-triketone and bridging chiral diphosphine and diamines are excellent catalysts for this reaction giving enantioselectivites considerably higher than the monometallic catalysts. Enantioselectivities were more than 50% for most olefins tested. The highest optical purities were 94% ee for propene and 93% ee for allylphenyl ether. A useful feature of this asymmetric synthesis is the fact it is a net air oxidation. (C) 2000 Elsevier Science S.A. All rights reserved.
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页码：50 / 60
页数：11
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