Combination stroke therapy: easy as APC?

被引：10

作者：

Lo, EH

机构：

[1] Massachusetts Gen Hosp, Dept Radiol, Neuroprotect Res Lab, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Neurol, Neuroprotect Res Lab, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Program Neurosci, Boston, MA 02115 USA

来源：

NATURE MEDICINE | 2004年 / 10卷 / 12期

关键词：

D O I：

10.1038/nm1204-1295

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The US Food and Drug Administration has approved only one therapy for ischemic stroke, recombinant tissue plasminogen activator (tPA), which can increase blood flow to damaged brain tissue—but it can also have severe side effects and must be administered shortly after stroke. Experiments combining the drug with activated protein C (APC) may provide a solution (pages 1379–1383).

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收藏

页码：1295 / 1296

页数：3

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