A portable device for small animal SPECT imaging in clinical gamma-cameras

被引：3

作者：

Aguiar, P. ^{[1
,2
]}

Silva-Rodriguez, J. ^{[1
,7
]}

Gonzalez-Castano, D. M. ^{[3
]}

Pino, F. ^{[4
,5
]}

Sanchez, M. ^{[1
]}

Herranz, M. ^{[1
]}

Iglesias, A. ^{[6
,7
]}

Lois, C. ^{[3
,8
]}

Ruibal, A. ^{[1
,2
,9
]}

机构：

[1] CHUS, IDIS, Dept Nucl Med, Mol Imaging & Oncol Grp, Santiago De Compostela 15706, Spain

[2] Univ Santiago de Compostela USC, Fac Med, Mol Imaging Grp, Santiago De Compostela 15782, Spain

[3] Univ Santiago de Compostela USC, Radiat Phys Lab, Santiago De Compostela 15782, Spain

[4] Univ Barcelona, Fac Med, Biophys & Bioengn Unit, Barcelona 08036, Spain

[5] Inst Catala Oncol, Dept Med Phys, Barcelona 08907, Spain

[6] Univ Vigo, Dept Mech Engn, CIMA, Vigo 36200, Spain

[7] Univ Santiago de Compostela USC, Fac Phys, L2A2, Santiago De Compostela 15782, Spain

[8] MIT, Madrid MIT Vis Consortium, Boston, MA 02139 USA

[9] Fdn Tejerina, Madrid 28003, Spain

来源：

JOURNAL OF INSTRUMENTATION | 2014年 / 9卷

关键词：

Image reconstruction in medical imaging; Gamma camera; SPECT; PET PET/ CT; coronary CT angiography (CTA); Medical-image reconstruction methods and algorithms; computer-aided diagnosis; PINHOLE SPECT; SYSTEM;

D O I：

10.1088/1748-0221/9/07/P07004

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Molecular imaging is reshaping clinical practice in the last decades, providing practitioners with non-invasive ways to obtain functional in-vivo information on a diversity of relevant biological processes. The use of molecular imaging techniques in preclinical research is equally beneficial, but spreads more slowly due to the difficulties to justify a costly investment dedicated only to animal scanning. An alternative for lowering the costs is to repurpose parts of old clinical scanners to build new preclinical ones. Following this trend, we have designed, built, and characterized the performance of a portable system that can be attached to a clinical gamma-camera to make a preclinical single photon emission computed tomography scanner. Our system offers an image quality comparable to commercial systems at a fraction of their cost, and can be used with any existing gamma-camera with just an adaptation of the reconstruction software.

引用

页数：15

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