Ruthenium-Catalyzed, Keto-Directed, Site-Selective C-H Activation of Diverse Chromanones with Alkenes

被引：16

作者：

Bakthadoss, Manickam ^{[1
]}

Kumar, Polu Vijay ^{[1
]}

Reddy, Tatiparthi Sushmitha ^{[1
]}

机构：

[1] Pondicherry Univ, Dept Chem, Pondicherry 605014, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 2017卷 / 30期

关键词：

C-H activation; Directing groups; Site selectivity; Heterocycles; Fused-ring systems; ANTI-AIDS AGENTS; ARTOCARPUS-HETEROPHYLLUS; OXIDATIVE ALKENYLATION; EFFICIENT SYNTHESIS; BOND FORMATION; FLAVONOIDS; PALLADIUM; FUNCTIONALIZATION; ANTIOXIDANT; OLEFINATION;

D O I：

10.1002/ejoc.201700513

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and versatile approach towards the synthesis of highly functionalized C5-alkenylated chromanones in good yields in a regio- and stereoselective fashion was explored. This reaction takes place through chelation-aided oxidative coupling of keto-directed, site-selective C-H activation by using chromanones with alkenes in the presence of a ruthenium catalyst under mild conditions.

引用

页码：4439 / 4444

页数：6

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