The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata

被引：47

作者：

Meah, Nekma ^{[1
]}

Wall, Dmitri ^{[2
,3
]}

York, Katherine ^{[4
]}

Bhoyrul, Bevin ^{[1
]}

Bokhari, Laita ^{[1
]}

Asz-Sigall, Daniel ^{[5
]}

Bergfeld, Wilma F. ^{[6
]}

Betz, Regina C. ^{[7
,8
]}

Blume-Peytavi, Ulrike ^{[9
]}

Callender, Valerie ^{[10
]}

Chitreddy, Vijaya ^{[1
]}

Combalia, Andrea ^{[11
]}

Cotsarelis, George ^{[12
]}

Craiglow, Brittany ^{[13
,14
]}

Donovan, Jeff ^{[15
]}

Eisman, Samantha ^{[1
]}

Farrant, Paul ^{[16
]}

Green, Jack ^{[17
]}

Grimalt, Ramon ^{[18
]}

Harries, Matthew ^{[19
,20
,21
,22
]}

Hordinsky, Maria ^{[23
]}

Irvine, Alan D. ^{[24
]}

Itami, Satoshi ^{[25
]}

Jolliffe, Victoria ^{[26
]}

King, Brett ^{[27
]}

Lee, Won-Soo ^{[28
]}

McMichael, Amy ^{[29
]}

Messenger, Andrew ^{[30
]}

Mirmirani, Paradi ^{[31
]}

Olsen, Elise ^{[32
]}

Orlow, Seth J. ^{[33
]}

Piraccini, Bianca Maria ^{[34
]}

Rakowska, Adriana ^{[35
]}

Reygagne, Pascal ^{[36
]}

Roberts, Janet L. ^{[37
]}

Rudnicka, Lidia ^{[35
]}

Shapiro, Jerry ^{[33
]}

Sharma, Pooja ^{[1
]}

Tosti, Antonella ^{[38
]}

Vogt, Annika ^{[9
]}

Wade, Martin ^{[39
]}

Yip, Leona ^{[40
]}

Zlotogorski, Abraham ^{[41
]}

Sinclair, Rodney D. ^{[1
]}

机构：

[1] Sinclair Dermatol, 2 Wellington Parade, East Melbourne, Vic 3002, Australia

[2] Hair Restorat Blackrock, Dublin, Ireland

[3] Natl & Int Skin Registry Solut NISR, Dublin, Ireland

[4] Netcare Greenacres Hosp, Port Elizabeth, South Africa

[5] Dermalomas Clin, Mexico City, DF, Mexico

[6] Cleveland Clin, Main Campus, Cleveland, OH USA

[7] Univ Bonn, Sch Med, Inst Human Genet, Bonn, Germany

[8] Univ Hosp, Bonn, Germany

[9] Charite Univ Med Berlin, Dept Dermatol Venerol & Allergol, Clin Res Ctr Hair & Skin Sci, Berlin, Germany

[10] Callender Dermatol & Cosmet Ctr, Glenn Dale, MD USA

[11] Hosp Clin Barcelona, Dept Dermatol, Barcelona, Spain

[12] Univ Penn, Sch Med, Dept Dermatol, Philadelphia, PA 19104 USA

[13] Dermatol Phys Connecticut, Fairfield, CT USA

[14] Yale Dept Dermatol, New Haven, CT USA

[15] Donovan Hair Clin, Whistler, BC, Canada

[16] Brighton & Sussex Univ Hosp Trust, Brighton, E Sussex, England

[17] St Vincents Hosp, Dept Dermatol, Melbourne, Vic, Australia

[18] Univ Int Catalunya, Fac Med & Ciencies Salut, Josep Trueta S-N, Barcelona 08195, Spain

[19] Univ Manchester, Ctr Dermatol Res, MAHSC, Manchester, Lancs, England

[20] NIHR Manchester, Manchester, Lancs, England

[21] Biomed Res Ctr, Manchester, Lancs, England

[22] Salford Royal NHS Fdn Trust, Dermatol Ctr, Manchester, Lancs, England

[23] Univ Minnesota, Med Sch, Dept Dermatol, Minneapolis, MN USA

[24] Trinity Coll Dublin, Clin Med, Dublin, Ireland

[25] Oita Univ, Dept Dermatol, Yufu City, Japan

[26] Blizard Inst, Ctr Cell Biol & Cutaneous Res, London, England

[27] Yale Sch Med, New Haven, CT USA

[28] Yonsei Univ, Dept Dermatol, Wonju Coll Med, Wonju, South Korea

[29] Wake Forest Univ, Bowman Gray Sch Med, Winston Salem, NC USA

[30] Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England

[31] Kaiser Permanente Vallejo, Dept Dermatol, Vallejo, CA USA

[32] Clin 3K, Duke Dermatol Clin, Durham, NC USA

[33] NYU, Grossman Sch Med, Ronald O Perelman Dept Dermatol, New York, NY USA

[34] Alma Mater Studiorum Univ Bologna, Dermatol Unit, Dept Expt Diagnost & Specialty Med Dimes, Int Relat, Bologna, Italy

[35] Med Univ Warsaw, Dept Dermatol, Warsaw, Poland

[36] Hop St Louis, Ctr Sante Sabouraud, Paris, France

[37] Northwest Dermatol Inst Portland, Portland, OR USA

[38] Univ Miami, Miller Sch Med, Dr Phillip Frost Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA

[39] London Skin & Hair Clin, London, England

[40] Skin Partners Specialist Dermatologists, Brisbane, Qld, Australia

[41] Hebrew Univ Jerusalem, Fac Med, Hadassah Med Ctr, Dept Dermatol, Jerusalem, Israel

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2021年 / 84卷 / 06期

关键词：

alopecia areata; assessment; consensus; Delphi; guideline; DELPHI; MANAGEMENT; ASSOCIATION; GUIDELINES; PROTOCOL;

D O I：

10.1016/j.jaad.2020.09.028

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: We previously reported the Alopecia Areata Consensus of Experts study, which presented results of an international expert opinion on treatments for alopecia areata. Objective: To report the results of the Alopecia Areata Consensus of Experts international expert opinion on diagnosis and laboratory evaluation for alopecia areata. Methods: Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Consensus threshold was set at greater than or equal to 66%. Results: Of 148 questions, expert consensus was achieved in 82 (55%). Round 1 consensus was achieved in 10 of 148 questions (7%). Round 2 achieved consensus in 47 of 77 questions (61%). The final face-to-face achieved consensus in 25 of 32 questions (78%). Consensus was greatest for laboratory evaluation (12 of 14 questions [86%]), followed by diagnosis (11 of 14 questions [79%]) of alopecia areata. Overall, etiopathogenesis achieved the least category consensus (31 of 68 questions [46%]). Limitations: The study had low representation from Africa, South America, and Asia. Conclusion: There is expert consensus on aspects of epidemiology, etiopathogenesis, clinical features, diagnosis, laboratory evaluation, and prognostic indicators of alopecia areata. The study also highlights areas where future clinical research could be directed to address unresolved hypotheses in alopecia areata patient care.

引用

页码：1594 / 1601

页数：8

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