Osteoporosis management in hematologic stem cell transplant recipients: Executive summary

被引：19

作者：

Kendler, D. L. ^{[1
]}

Body, J. J. ^{[2
]}

Brandi, M. L. ^{[3
]}

Broady, R. ^{[4
]}

Cannata-Andia, J. ^{[5
]}

Cannata-Ortiz, M. J. ^{[6
]}

El Maghraoui, A. ^{[7
]}

Guglielmi, G. ^{[8
]}

Hadji, P. ^{[9
]}

Pierroz, D. D. ^{[10
]}

de Villiers, T. J. ^{[11
,12
]}

Ebeling, P. R. ^{[13
]}

Rizzoli, R. ^{[14
,15
]}

机构：

[1] Univ British Columbia, Div Endocrinol, Dept Med, Vancouver, BC, Canada

[2] Univ Libre Bruxelles, CHU Brugmann, Brussels, Belgium

[3] Univ Florence, Dept Surg & Translat Med, Mineral & Bone Metab Unit, Florence, Italy

[4] Univ British Columbia, Div Hematol, Dept Med, Vancouver, BC, Canada

[5] Univ Oviedo, Hosp Univ Cent Asturias, Serv Metab Oseo & Mineral, Oviedo, Spain

[6] IIS Princesa, Hosp Princesa, Dept Haematol, Madrid, Spain

[7] Mohammed V Souissi Univ, Dept Rheumatol, Mil Hosp Mohammed V, Rabat, Morocco

[8] Univ Foggia, Dept Radiol, Foggia, Italy

[9] Frankfurt Ctr Bone Hlth, Frankfurt, Germany

[10] Int Osteoporosis Fdn IOF, Nyon, Switzerland

[11] Stellenbosch Univ, Fac Hlth Sci, Dept Gynaecol, Cape Town, South Africa

[12] Mediclin Panorama, Cape Town, South Africa

[13] Monash Univ, Dept Med, Sch Clin Sci, Clayton, Vic, Australia

[14] Geneva Univ Hosp, Div Bone Dis, Geneva, Switzerland

[15] Fac Med, CH-1211 Geneva 14, Switzerland

来源：

JOURNAL OF BONE ONCOLOGY | 2021年 / 28卷

关键词：

Hematopoietic stem cell; Transplantation; Bone loss; Bone marrow; Fracture; Bone mineral density; BONE-MINERAL DENSITY; VITAMIN-D DEFICIENCY; LONG-TERM SURVIVORS; ZOLEDRONIC ACID; PREVENTION; WOMEN;

D O I：

10.1016/j.jbo.2021.100361

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Treatment advances have reduced the adverse events associated with hematopoietic stem cell transplant (HSCT) and led to an increased number of transplants performed. HSCT patients are living longer with concerns on long-term outcomes. Bone fragility and fracture are at the forefront for longterm morbidities post-HSCT. Results: In HSCT recipients, evidence has accumulated to support recommendations for more extensive monitoring of bone fragility and more appropriate administration of osteoporosis pharmacotherapies for patients at high risk of bone loss and/or fracture. Cnclusion: This executive summary reports and summarizes the main recommendations published previously, including bone assessment, dietary and lifest yle recommendations and osteoporosis medication. (c) 2021 Published by Elsevier GmbH. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).

引用

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