Latest Advancements on Serotonin and Dopamine Transporters in Lymphocytes

被引：26
作者：
Marazziti, Donatella [1 ]
Consoli, Giorgio [1 ]
Masala, Irene [1 ]
Dell'Osso, Mario Catena [1 ]
Baroni, Stefano [1 ]
机构：
[1] Univ Pisa, Dipartimento Psichiatria Neurobiol Farmacol & Bio, I-56100 Pisa, Italy
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2010年 / 10卷 / 01期
关键词：
Serotonin; dopamine; serotonin transporter; dopamine transporter; lymphocytes; antidepressants; immune system; PROTEIN-KINASE-C; PERIPHERAL-BLOOD LYMPHOCYTES; H-3 PAROXETINE BINDING; OBSESSIVE-COMPULSIVE DISORDER; HUMAN RESTING LYMPHOCYTES; SINGLE-SITE MODEL; CD8(+) T-CELLS; MAJOR DEPRESSION; IN-VITRO; PARKINSONS-DISEASE;
D O I：
10.2174/138955710791112587
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Different data show that circulating lymphocytes possess functional serotonin and dopamine transporters (SERT and DAT, respectively). This papers aims to review most of the available literature on this topic, while highlighting the possible role of SERT and DAT, as well as that of their substrates including antidepressants on the immune system.
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收藏
页码：32 / 40
页数：9
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