Inhibition of osteoporosis due to restricted food intake by the fish oils DHA and EPA and perilla oil in the rat

被引：30

作者：

Sun, L

Tamaki, H

Ishimaru, T

Teruya, T

Ohta, Y

Katsuyama, N

Chinen, I

机构：

[1] Univ Ryukyus, Lab Appl Biochem, Fac Agr, Okinawa 9030213, Japan

[2] Musashi Jr High Sch, Oita 8730404, Japan

[3] Univ Ryukyus, Fac Med, Okinawa 9030213, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2004年 / 68卷 / 12期

关键词：

osteoporosis; docosahesaenoic acid (DHA); eicosapentaenoic acid (EPA); deoxypyrisinolin; restricted food;

D O I：

10.1271/bbb.68.2613

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Seven-week old female rats fed restricted foods including the fish oils Docosahesaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) and perilla oil with food intake decreased by 50%, had increases of fracture force and bone mineral density (BMD) and decreases in levels of Deoxypiridinoline (Dpd) and Calcium (Ca) in the urine, compared with those of rats with osteoporosis due to restricted soy bean oil food intake. Therefore, the fish oils DHA and EPA and perilla oil depressed excretion of urinary Ca and inhibited osteoporosis due to restricted food intake.

引用

页码：2613 / 2615

页数：3

共 15 条

[1]

AVIOLI LV, 1993, J BONE MINER RES, V8, pS511

[2]

Baggio B, 1996, J AM SOC NEPHROL, V7, P613

[3] THE PROTECTIVE ROLE OF EICOSAPENTAENOIC ACID [EPA] IN THE PATHOGENESIS OF NEPHROLITHIASIS [J].