Regioselective electrophilic trifluoromethylation of substituted anilines and derivatives in superacid

被引：19

作者：

Debarge, S ^{[1
]}

Violeau, B ^{[1
]}

Bendaoud, N ^{[1
]}

Jouannetaud, MP ^{[1
]}

Jacquesy, JC ^{[1
]}

机构：

[1] Lab Synthese & Reactivite Subst Nat, UMR 6514, F-86022 Poitiers, France

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(03)00124-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In a one pot procedure, treatment of chloro or methyl substituted acetanilides in HF/SbF5/CCl4 followed by addition of HF/pyridine yields trifluoromethyl derivatives with high regioselectivity. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1747 / 1750

页数：4

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