Sterolomics: State of the art, developments, limitations and challenges

被引：7

作者：

Griffiths, William J. ^{[1
]}

Wang, Yuqin ^{[1
]}

机构：

[1] Swansea Univ, Med Sch, Singleton Pk, Swansea SA2 8PP, W Glam, Wales

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 2017年 / 1862卷 / 08期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Sterol; Cholesterol; 7-Dehydrocholesterol; Oxysterol; Free radical reaction; Mass spectrometry; MASS-SPECTROMETRY; CHOLESTEROL-METABOLISM; HUMAN PLASMA; OXYSTEROLS; OXIDATION; TISSUES; BRAIN; ACIDS;

D O I：

10.1016/j.bbalip.2017.03.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sterolomics can be thought of as the quantitative determination of the entire complement of molecules based on the cyclopentanoperhydrophenanthrene skeleton in a system. Mass spectrometry is the dominant analytical technology employed. In this article we highlight some pitfalls in analysis, data interpretation and annotation. We give our opinion on how some of these pitfalls can best be avoided. This article is part of a Special Issue entitled: BBALIP_Lipidomics Opinion Articles edited by Sepp Kohlwein.

引用

页码：771 / 773

页数：3

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