NEURONAVIGATED HIGH-FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION FOR CHRONIC POST-STROKE DYSPHAGIA: A RANDOMIZED CONTROLLED STUDY

被引:56
作者
Cheng, Ivy K. Y. [1 ]
Chan, Karen M. K. [1 ]
Wong, Chun-sing [2 ]
Li, Leonard S. W. [3 ]
Chiu, Karen M. Y. [1 ]
Cheung, Raymond T. F. [4 ]
Yiu, Edwin M. L. [1 ]
机构
[1] Univ Hong Kong, Div Speech & Hearing Sci, Pokfulam, Hong Kong, Peoples R China
[2] Univ Hong Kong, Div Diagnost Radiol, Pokfulam, Hong Kong, Peoples R China
[3] Univ Hong Kong, Dept Med, Pokfulam, Hong Kong, Peoples R China
[4] Univ Hong Kong, Dept Neurol, Pokfulam, Hong Kong, Peoples R China
关键词
neurorehabilitation; dysphagia; repetitive transcranial magnetic stimulation; stroke; RESIDUE RATIO SCALE; STROKE PATIENTS; OROPHARYNGEAL DYSPHAGIA; RTMS; DIAGNOSIS; RECOVERY; SWALLOW; COMPLICATIONS; MECHANISMS; SUBSEQUENT;
D O I
10.2340/16501977-2235
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Objective: There are potential benefits of repetitive transcranial magnetic stimulation (rTMS) in improving swallowing functions after stroke; however, few studies have been performed in the chronic stroke population. This study aims to distil the key effects of rTMS on swallowing functions and swallowing-related quality of life. Methods: Twenty-two participants with chronic poststroke dysphagia were randomly assigned into active or sham rTMS groups. Seven participants withdrew from the study, thus data from 15 participants (mean age 64.6 years) were analysed. Participants received 3,000 pulses of 5 Hz rTMS (active: n = 11; sham: n = 4) on the tongue area of the motor cortex for 10 days over a period of 2 weeks. All participants were assessed 1 week before, and 2 months, 6 months and 12 months after stimulation. Outcomes were measured by a videofluoroscopic swallowing study, swallowing-related quality-of-life questionnaire and Iowa Oral Performance Instrument. Results: No statistically significant effects were identified for any outcome measures. Conclusion: This study indicates that 5 Hz rTMS applied over the tongue area of the motor cortex is not effective for improving swallowing function in individuals with chronic post-stroke dysphagia. Possible explanations for these non-significant results are discussed. Future studies should explore the potential of the current protocol in conjunction with conventional dysphagia therapy.
引用
收藏
页码:475 / 481
页数:7
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