Al(OTf)3 as a highly efficient catalyst for the rapid acetylation of alcohols, phenols and thiophenols under solvent-free conditions

被引：81

作者：

Kamal, Ahmed ^{[1
]}

Khan, M. Naseer A. ^{[1
]}

Reddy, K. Srinivasa ^{[1
]}

Srikanth, Y. V. V. ^{[1
]}

Krishnaji, T. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Biotransformat Lab, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 22期

关键词：

D O I：

10.1016/j.tetlet.2007.03.162

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aluminium triflate (0.01-0.1 mol %) was found to be an efficient catalyst for the acylation of alcohols, phenols, thiols and sugars with acetic anhydride in high yields under solvent-free conditions in a short reaction time at room temperature. Racemization of optically active alcohols and epimerization of sugars were not observed. The acylation efficacy of various acyl donors was also investigated. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：3813 / 3818

页数：6

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