INFLIXIMAB THERAPY AND THE CENTRAL NERVOUS DEMYELINATION IN PATIENTS WITH KAWASAKI DISEASE

被引:1
作者
Sagara, Yuka [1 ]
Muneuchi, Jun [1 ]
Shimabukuro, Wataru [1 ]
Joo, Masahiko [1 ]
Yoshino, Miwa [1 ]
Nakamura, Ryoko [1 ]
Yoneda, Toru [1 ]
Sugitani, Yuichiro [1 ]
Watanabe, Mamie [1 ]
Mizushima, Akira [2 ]
Takahashi, Yasuhiko [1 ]
机构
[1] Japan Commun Healthcare Org Kyushu Hosp, Dept Pediat, Kitakyushu, Fukuoka, Japan
[2] Japan Commun Healthcare Org Kyushu Hosp, Dept Radiol, Kitakyushu, Fukuoka, Japan
关键词
Kawasaki disease; infliximab; intravenous immunoglobulin; complication; central nervous system; ALPHA THERAPY; PREDICTION;
D O I
10.1097/INF.0000000000002296
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We performed brain magnetic resonance imaging in 14 patients with Kawasaki disease who were treated with infliximab (IFX) at 56 months of age (32-62 months of age) and 23 months (5-35 months) after IFX therapy. Magnetic resonance imaging showed no finding of the central nervous demyelination. IFX therapy is not related to central nervous demyelination in patients with Kawasaki disease.
引用
收藏
页码:E185 / E187
页数:4
相关论文
共 9 条
  • [1] Infliximab Treatment of Intravenous Immunoglobulin-Resistant Kawasaki Disease
    Burns, Jane C.
    Best, Brookie M.
    Mejias, Asuncion
    Mahony, Lynn
    Fixler, David E.
    Jafri, Hasan S.
    Melish, Marian E.
    Jackson, Mary Anne
    Asmar, Basim I.
    Lang, David J.
    Connor, James D.
    Capparelli, Edmund V.
    Keen, Monica L.
    Mamun, Khalid
    Keenan, Gregory F.
    Ramilo, Octavio
    [J]. JOURNAL OF PEDIATRICS, 2008, 153 (06) : 833 - 838
  • [2] Infliximab treatment for refractory Kawasaki syndrome
    Burns, JC
    Mason, WH
    Hauger, SB
    Janai, H
    Bastian, JF
    Wohrley, JD
    Balfour, I
    Shen, CA
    Michel, ED
    Shulman, ST
    Melish, ME
    [J]. JOURNAL OF PEDIATRICS, 2005, 146 (05) : 662 - 667
  • [3] Prediction of resistance to intravenous immunoglobulin treatment in patients with Kawasaki disease
    Egami, Kimiyasu
    Muta, Hiromi
    Ishii, Masahiro
    Suda, Kenji
    Sugahara, Yoko
    Iemura, Motofumi
    Matsuishi, Toyojiro
    [J]. JOURNAL OF PEDIATRICS, 2006, 149 (02) : 237 - 240
  • [4] Demyelination and other neurological adverse events after anti-TNF therapy
    Kaltsonoudis, Evripidis
    Voulgari, Paraskevi V.
    Konitsiotis, Spyridon
    Drosos, Alexandros A.
    [J]. AUTOIMMUNITY REVIEWS, 2014, 13 (01) : 54 - 58
  • [5] Prediction of intravenous immunoglobulin unresponsiveness in patients with Kawasaki disease
    Kobayashi, Tohru
    Inoue, Yoshinari
    Takeuchi, Kazuo
    Okada, Yasunori
    Tamura, Kazushi
    Tomomasa, Takeshi
    Kobayashi, Tomio
    Morikawa, Akihiro
    [J]. CIRCULATION, 2006, 113 (22) : 2606 - 2612
  • [6] Mohan N, 2001, ARTHRITIS RHEUM-US, V44, P2862, DOI 10.1002/1529-0131(200112)44:12<2862::AID-ART474>3.0.CO
  • [7] 2-W
  • [8] Magnetic resonance studies of brain lesions in patients with Kawasaki disease
    Muneuchi, J
    Kusuhara, K
    Kanaya, Y
    Ohno, T
    Furuno, K
    Kira, R
    Mihara, F
    Hara, T
    [J]. BRAIN & DEVELOPMENT, 2006, 28 (01) : 30 - 33
  • [9] Pattern of demyelination occurring during anti-TNF-α therapy: a French national survey
    Seror, Raphaele
    Richez, Christophe
    Sordet, Christelle
    Rist, Stephanie
    Gossec, Laure
    Direz, Guillaume
    Houvenagel, Eric
    Berthelot, Jean-Marie
    Pagnoux, Christian
    Dernis, Emmanuelle
    Melac-Ducamp, Sylvie
    Bouvard, Beatrice
    Asquier, Caroline
    Martin, Antoine
    Puechal, Xavier
    Mariette, Xavier
    [J]. RHEUMATOLOGY, 2013, 52 (05) : 868 - 874