Is trehalose-6-phosphate a regulator of sugar metabolism in plants?

被引：72

作者：

Eastmond, PJ ^{[1
]}

Li, Y ^{[1
]}

Graham, IA ^{[1
]}

机构：

[1] Univ York, Dept Biol, Ctr Novel Agr Prod, York YO10 5YW, N Yorkshire, England

来源：

JOURNAL OF EXPERIMENTAL BOTANY | 2003年 / 54卷 / 382期

基金：

英国生物技术与生命科学研究理事会;

关键词：

Arabidopsis; trehalose; trehalose-6-phosphate; trehalose-6-phosphate synthase;

D O I：

10.1093/jxb/erg039

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

It has recently emerged that many higher plants can synthesize trace amounts of trehalose. In arabidopsis disruption of the first step of trehalose synthesis, catalysed by trehalose-6-phosphate synthase (TPS), has lethal consequences, demonstrating an important physiological role. It is not yet clear what the precise function of trehalose synthesis is, but there is mounting evidence that trehalose-6-phosphate is implicated in the regulation of sugar metabolism. Further work is necessary to confirm this hypothesis and determine the underlying mechanism.

引用

页码：533 / 537

页数：5

共 32 条

[1] Purification of the trehalase GMTRE1 from soybean nodules and cloning of its cDNA.: GMTRE1 is expressed at a low level in multiple tissues [J].

Aeschbacher, RA ;

Müller, J ;

Boller, T ;

Wiemken, A .

PLANT PHYSIOLOGY, 1999, 119 (02) :489-495

[2] Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex [J].

Bell, W ;

Sun, WN ;

Hohmann, S ;

Wera, S ;

Reinders, A ;

De Virgilio, C ;

Wiemken, A ;

Thevelein, JM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (50) :33311-33319

[3] Isolation and molecular characterization of the Arabidopsis TPS1 gene, encoding trehalose-6-phosphate synthase [J].

Blázquez, MA ;

Santos, E ;

Flores, CL ;

Martínez-Zapater, JM ;

Salinas, J ;

Gancedo, C .

PLANT JOURNAL, 1998, 13 (05) :685-689

[4] TREHALOSE-6-PHOSPHATE, A NEW REGULATOR OF YEAST GLYCOLYSIS THAT INHIBITS HEXOKINASES [J].

BLAZQUEZ, MA ;

LAGUNAS, R ;

GANCEDO, C ;

GANCEDO, JM .

FEBS LETTERS, 1993, 329 (1-2) :51-54

[5] Expression of Escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis [J].

Bonini, BM ;

van Vaeck, C ;

Larsson, C ;

Gustafsson, L ;

Ma, PS ;

Winderickx, J ;

van Dijck, P ;

Thevelein, JM .

BIOCHEMICAL JOURNAL, 2000, 350 :261-268

[6]

CROWE JH, 1992, ANNU REV PHYSIOL, V54, P579, DOI 10.1146/annurev.ph.54.030192.003051

[7] Trehalose-6-phosphate synthase 1, which catalyses the first step in trehalose synthesis, is essential for Arabidopsis embryo maturation [J].

Eastmond, PJ ;

van Dijken, AJH ;

Spielman, M ;

Kerr, A ;

Tissier, AF ;

Dickinson, HG ;

Jones, JDG ;

Smeekens, SC ;

Graham, IA .

PLANT JOURNAL, 2002, 29 (02) :225-235

[8]

Elbein A D, 1974, Adv Carbohydr Chem Biochem, V30, P227, DOI 10.1016/S0065-2318(08)60266-8

[9] SACCHAROMYCES-CEREVISIAE MUTANTS PROVIDE EVIDENCE OF HEXOKINASE PII AS A BIFUNCTIONAL ENZYME WITH CATALYTIC AND REGULATORY DOMAINS FOR TRIGGERING CARBON CATABOLITE REPRESSION [J].

ENTIAN, KD ;

FROHLICH, KU .

JOURNAL OF BACTERIOLOGY, 1984, 158 (01) :29-35

[10] Sensing trehalose biosynthesis in plants [J].

Goddijn, O ;

Smeekens, S .

PLANT JOURNAL, 1998, 14 (02) :143-146

← 1 2 3 4 →